• Olink® Target 96 Cardiovascular Panels

    Thoroughly validated, high-performance protein biomarker panels for cardiovascular and cardiometabolic studies.

    Olink® Target 96 panels specialize in key disease areas and important biological processes, and accelerate targeted protein biomarker research through high-multiplex immunoassays, providing uncompromised data quality and performance.

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    Key features & benefits

    • Allows for simultaneous analysis of 92 protein biomarkers
    • Uses only 1 µL of biological sample
    • Exceptional data quality through relative (NPX) quantification
    • qPCR readout with unparalleled sensitivity, specificity, and precision
    • All assays are subject to Olink’s strict technical validation and quality control procedures

    Olink Target 96 Cardiovascular Panels offer a broad selection of proteins associated with biological functions linked to cardiovascular diseases. Categorization of the proteins included in the panel was carried out via referral to widely used public-access bioinformatic databases, including Uniprot, Human Protein Atlas, Gene Ontology (GO) and DisGeNET.

    Target

    Accelerate targeted protein biomarker research through high-multiplex immunoassays, providing uncompromised data quality and performance.
    Learn more about the Olink Target platform.

    Olink® Target 96 & 48

    How does it work?

    The unique technology behind the Olink platforms, Proximity Extension Assay (PEA) technology, is an innovative dual recognition, DNA-coupled methodology providing exceptional readout specificity. PEA enables high multiplex, rapid throughput biomarker analysis without compromising on data quality.

    PEA-image

    Read more about how Olink technology delivers this scale of multiplexing and sample throughput without compromising on data quality or assay robustness.

    Proximity Extension Assay (PEA) technology

    The Olink biomarker assay panels are available with the flexibility to best suit your needs. You can choose whether to purchase the panels as kits and run them in your own lab, or send your sample the experts at one of the many trained service providers around the world offering sample analysis service.

    Panels

    Olink Target 96 Cardiovascular II ( 92 )

    This panel contains known human cardiovascular and inflammatory markers as well as some exploratory human proteins with great potential as new CVD markers.

    The biomarker pages linked to below include calibrator curves that show the performance of each assay with the estimated sensitivity and dynamic range parameters indicated.

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    2,4-dienoyl-CoA reductase, mitochondrial (DECR1)
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    A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAMTS13)
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    Advanced glycosylation end product-specific receptor (AGER)
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    Agouti-related protein (AGRP)
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    Alpha-L-iduronidase (IDUA)
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    Angiopoietin-1 (ANGPT1)
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    Angiopoietin-1 receptor (TEK)
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    Angiotensin-converting enzyme 2 (ACE2)
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    Bone morphogenetic protein 6 (BMP6)
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    Brother of CDO (BOC)
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    C-C motif chemokine 17 (CCL17)
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    C-C motif chemokine 3 (CCL3)
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    CD40 ligand (CD40LG)
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    Carbonic anhydrase 5A, mitochondrial (CA5A)
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    Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8)
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    Cathepsin L1 (CTSL)
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    Chymotrypsin-C (CTRC)
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    Cobalamin binding intrinsic factor (CBLIF)
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    Decorin (DCN)
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    Dickkopf-related protein 1 (DKK1)
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    Fatty acid-binding protein, intestinal (FABP2)
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    Fibroblast growth factor 21 (FGF21)
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    Fibroblast growth factor 23 (FGF23)
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    Follistatin (FST)
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    Galectin-9 (LGALS9)
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    Gastrotropin (FABP6)
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    Growth-regulated alpha protein (CXCL1)
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    Growth/differentiation factor 2 (GDF2)
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    Heat shock protein beta-1 (HSPB1)
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    Heme oxygenase 1 (HMOX1)
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    Hepatitis A virus cellular receptor 1 (HAVCR1)
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    Hydroxyacid oxidase 1 (HAO1)
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    Integrin beta-1-binding protein 2 (ITGB1BP2)
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    Interleukin-1 receptor antagonist protein (IL1RN)
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    Interleukin-1 receptor-like 2 (IL1RL2)
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    Interleukin-17D (IL17D)
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    Interleukin-18 (IL18)
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    Interleukin-27 (EBI3_IL27)
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    Interleukin-4 receptor subunit alpha (IL4R)
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    Interleukin-6 (IL6)
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    Kit ligand (KITLG)
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    Lactoylglutathione lyase (GLO1)
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    Leptin (LEP)
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    Lipoprotein lipase (LPL)
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    Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B)
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    Lymphotactin (XCL1)
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    Macrophage metalloelastase (MMP12)
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    Macrophage receptor MARCO (MARCO)
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    Matrilysin (MMP7)
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    NF-kappa-B essential modulator (IKBKG)
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    Natriuretic peptides B (NPPB)
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    Osteoclast-associated immunoglobulin-like receptor (OSCAR)
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    Oxidized low-density lipoprotein receptor 1 (OLR1)
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    P-selectin glycoprotein ligand 1 (SELPLG)
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    Pappalysin-1 (PAPPA)
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    Pentraxin-related protein PTX3 (PTX3)
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    Placenta growth factor (PGF)
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    Platelet-derived growth factor subunit B (PDGFB)
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    Poly [ADP-ribose] polymerase 1 (PARP1)
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    Polymeric immunoglobulin receptor (PIGR)
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    Pro-adrenomedullin (ADM)
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    Pro-interleukin-16 (IL16)
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    Programmed cell death 1 ligand 2 (PDCD1LG2)
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    Proheparin-binding EGF-like growth factor (HBEGF)
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    Prolargin (PRELP)
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    Prostasin (PRSS8)
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    Protein AMBP (AMBP)
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    Protein-glutamine gamma-glutamyltransferase 2 (TGM2)
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    Proteinase-activated receptor 1 (F2R)
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    Proto-oncogene tyrosine-protein kinase Src (SRC)
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    Renin (REN)
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    SLAM family member 5 (CD84)
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    SLAM family member 7 (SLAMF7)
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    Serine protease 27 (PRSS27)
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    Serine/threonine-protein kinase 4 (STK4)
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    Serpin A12 (SERPINA12)
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    Somatotropin (GH1)
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    Sortilin (SORT1)
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    Spondin-2 (SPON2)
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    Superoxide dismutase [Mn], mitochondrial (SOD2)
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    T-cell surface glycoprotein CD4 (CD4)
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    Thrombomodulin (THBD)
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    Thrombopoietin (THPO)
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    Thrombospondin-2 (THBS2)
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    Tissue factor (F3)
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    Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A)
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    Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
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    Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A)
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    Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B)
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    Tyrosine-protein kinase Mer (MERTK)
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    V-set and immunoglobulin domain-containing protein 2 (VSIG2)
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    Vascular endothelial growth factor D (VEGFD)
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    Olink Target 96 Cardiovascular III ( 92 )

    This panel contains known human cardiovascular and inflammatory markers as well as some exploratory human proteins with great potential as new CVD markers.

    The biomarker pages linked to below include calibrator curves that show the performance of each assay with the estimated sensitivity and dynamic range parameters indicated.

    The cardiovascular III panel uses a 1:100 dilution of sample, whereas our technical validation assays are performed in vitro using recombinant analytes. Technical validation data reported on the biomarker pages below, and in the data validation document for this panel are based on these in vitro assays. A multiplication factor of 100 should therefore be taken into consideration when comparing the addressable biological concentration to the in vitro validation data. Sample dilution guidelines can be found in the User Manual.

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    72 kDa type IV collagenase (MMP2)
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    Aminopeptidase N (ANPEP)
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    Azurocidin (AZU1)
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    Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2)
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    Bleomycin hydrolase (BLMH)
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    C-C motif chemokine 15 (CCL15)
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    C-C motif chemokine 16 (CCL16)
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    C-C motif chemokine 2 (CCL2)
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    C-C motif chemokine 24 (CCL24)
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    C-X-C motif chemokine 16 (CXCL16)
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    CD166 antigen (ALCAM)
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    Cadherin-5 (CDH5)
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    Carboxypeptidase A1 (CPA1)
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    Carboxypeptidase B (CPB1)
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    Caspase-3 (CASP3)
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    Cathepsin D (CTSD)
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    Cathepsin Z (CTSZ)
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    Chitinase-3-like protein 1 (CHI3L1)
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    Chitotriosidase-1 (CHIT1)
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    Collagen alpha-1(I) chain (COL1A1)
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    Complement component C1q receptor (CD93)
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    Contactin-1 (CNTN1)
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    Cystatin-B (CSTB)
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    E-selectin (SELE)
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    Elafin (PI3)
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    Ephrin type-B receptor 4 (EPHB4)
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    Epidermal growth factor receptor (EGFR)
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    Epithelial cell adhesion molecule (EPCAM)
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    Fatty acid-binding protein, adipocyte (FABP4)
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    Galectin-3 (LGALS3)
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    Galectin-4 (LGALS4)
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    Growth/differentiation factor 15 (GDF15)
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    Insulin-like growth factor-binding protein 1 (IGFBP1)
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    Insulin-like growth factor-binding protein 2 (IGFBP2)
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    Insulin-like growth factor-binding protein 7 (IGFBP7)
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    Integrin beta-2 (ITGB2)
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    Intercellular adhesion molecule 2 (ICAM2)
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    Interleukin-1 receptor type 1 (IL1R1)
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    Interleukin-1 receptor type 2 (IL1R2)
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    Interleukin-1 receptor-like 1 (IL1RL1)
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    Interleukin-17 receptor A (IL17RA)
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    Interleukin-18-binding protein (IL18BP)
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    Interleukin-2 receptor subunit alpha (IL2RA)
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    Interleukin-6 receptor subunit alpha (IL6R)
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    Junctional adhesion molecule A (F11R)
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    Kallikrein-6 (KLK6)
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    Low-density lipoprotein receptor (LDLR)
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    Matrix extracellular phosphoglycoprotein (MEPE)
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    Matrix metalloproteinase-9 (MMP9)
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    Metalloproteinase inhibitor 4 (TIMP4)
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    Myeloblastin (PRTN3)
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    Myeloperoxidase (MPO)
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    Myoglobin (MB)
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    N-terminal prohormone of brain natriuretic peptide (NT-proBNP)
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    Neurogenic locus notch homolog protein 3 (NOTCH3)
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    Osteopontin (SPP1)
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    P-selectin (SELP)
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    Peptidoglycan recognition protein 1 (PGLYRP1)
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    Plasminogen activator inhibitor 1 (SERPINE1)
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    Platelet endothelial cell adhesion molecule (PECAM1)
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    Platelet glycoprotein VI (GP6)
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    Platelet-derived growth factor subunit A (PDGFA)
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    Progranulin (GRN)
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    Proprotein convertase subtilisin/kexin type 9 (PCSK9)
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    Protein delta homolog 1 (DLK1)
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    Pulmonary surfactant-associated protein D (SFTPD)
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    Resistin (RETN)
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    Retinoic acid receptor responder protein 2 (RARRES2)
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    Scavenger receptor cysteine-rich type 1 protein M130 (CD163)
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    Secretoglobin family 3A member 2 (SCGB3A2)
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    Serum paraoxonase/lactonase 3 (PON3)
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    Spondin-1 (SPON1)
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    Stromelysin-1 (MMP3)
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    Tartrate-resistant acid phosphatase type 5 (ACP5)
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    Tissue factor pathway inhibitor (TFPI)
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    Tissue-type plasminogen activator (PLAT)
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    Transferrin receptor protein 1 (TFRC)
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    Trefoil factor 3 (TFF3)
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    Trem-like transcript 2 protein (TREML2)
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    Tumor necrosis factor ligand superfamily member 13B (TNFSF13B)
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    Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C)
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    Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)
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    Tumor necrosis factor receptor superfamily member 14 (TNFRSF14)
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    Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)
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    Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B)
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    Tumor necrosis factor receptor superfamily member 3 (LTBR)
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    Tumor necrosis factor receptor superfamily member 6 (FAS)
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    Tyrosine-protein kinase receptor UFO (AXL)
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    Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA)
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    Urokinase plasminogen activator surface receptor (PLAUR)
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    Urokinase-type plasminogen activator (PLAU)
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    von Willebrand factor (VWF)
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    Olink Target 96 Cardiometabolic ( 92 )

    The assays in this panel include proteins involved in key biological processes such as cellular metabolic process, cell adhesion, immune response and complement activation.

    The biomarker pages linked to below include calibrator curves that show the performance of each assay with the estimated sensitivity and dynamic range parameters indicated.

    The cardiometabolic panel uses a 1:2025 dilution of sample, whereas our technical validation assays are performed in vitro using recombinant analytes. Technical validation data reported on the biomarker pages below, and in the data validation document for this panel are based on these in vitro assays. A multiplication factor of 2025 should therefore be taken into consideration when comparing the addressable biological concentration to the in vitro validation data. Sample dilution guidelines can be found in the User Manual.

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    Angiogenin (ANG)
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    Angiopoietin-related protein 3 (ANGPTL3)
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    Apolipoprotein M (APOM)
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    Beta-Ala-His dipeptidase (CNDP1)
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    Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1)
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    C-C motif chemokine 14 (CCL14)
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    C-C motif chemokine 18 (CCL18)
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    C-C motif chemokine 5 (CCL5)
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    CD59 glycoprotein (CD59)
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    Cadherin-1 (CDH1)
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    Carbonic anhydrase 1 (CA1)
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    Carbonic anhydrase 3 (CA3)
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    Carbonic anhydrase 4 (CA4)
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    Cartilage acidic protein 1 (CRTAC1)
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    Cartilage oligomeric matrix protein (COMP)
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    Coagulation factor VII (F7)
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    Coagulation factor XI (F11)
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    Collagen alpha-1(XVIII) chain (COL18A1)
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    Complement C1q tumor necrosis factor-related protein 1 (C1QTNF1)
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    Complement C2 (C2)
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    Complement factor H-related protein 5 (CFHR5)
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    Complement receptor type 2 (CR2)
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    Cystatin-C (CST3)
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    Dipeptidyl peptidase 4 (DPP4)
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    EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1)
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    Endoglin (ENG)
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    Fetuin-B (FETUB)
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    Ficolin-2 (FCN2)
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    Glutaminyl-peptide cyclotransferase (QPCT)
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    Granulysin (GNLY)
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    Growth arrest-specific protein 6 (GAS6)
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    Hepatocyte growth factor receptor (MET)
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    Immunoglobulin lambda constant 2 (IGLC2)
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    Insulin-like growth factor-binding protein 3 (IGFBP3)
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    Insulin-like growth factor-binding protein 6 (IGFBP6)
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    Integrin alpha-M (ITGAM)
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    Intercellular adhesion molecule 1 (ICAM1)
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    Intercellular adhesion molecule 3 (ICAM3)
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    Interleukin-7 receptor subunit alpha (IL7R)
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    L-selectin (SELL)
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    Latent-transforming growth factor beta-binding protein 2 (LTBP2)
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    Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1)
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    Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2)
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    Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5)
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    Lithostathine-1-alpha (REG1A)
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    Liver carboxylesterase 1 (CES1)
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    Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A)
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    Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B)
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    Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1)
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    Lysosomal Pro-X carboxypeptidase (PRCP)
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    Mannose-binding protein C (MBL2)
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    Mast/stem cell growth factor receptor Kit (KIT)
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    Membrane cofactor protein (CD46)
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    Membrane primary amine oxidase (AOC3)
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    Metalloproteinase inhibitor 1 (TIMP1)
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    Microfibrillar-associated protein 5 (MFAP5)
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    Multiple epidermal growth factor-like domains protein 9 (MEGF9)
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    Neural cell adhesion molecule 1 (NCAM1)
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    Neural cell adhesion molecule L1-like protein (CHL1)
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    Neurogenic locus notch homolog protein 1 (NOTCH1)
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    Neuropilin-1 (NRP1)
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    Neutrophil defensin 1 (DEFA1_DEFA1B)
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    Neutrophil gelatinase-associated lipocalin (LCN2)
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    Nidogen-1 (NID1)
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    Oncostatin-M-specific receptor subunit beta (OSMR)
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    Peptidyl-glycine alpha-amidating monooxygenase (PAM)
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    Phospholipid transfer protein (PLTP)
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    Plasma serine protease inhibitor (SERPINA5)
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    Platelet glycoprotein Ib alpha chain (GP1BA)
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    Platelet-activating factor acetylhydrolase (PLA2G7)
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    Plexin-B2 (PLXNB2)
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    Procollagen C-endopeptidase enhancer 1 (PCOLCE)
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    Prolyl endopeptidase FAP (FAP)
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    Receptor-type tyrosine-protein phosphatase S (PTPRS)
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    Regenerating islet-derived protein 3-alpha (REG3A)
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    SPARC-like protein 1 (SPARCL1)
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    Serum amyloid A-4 protein (SAA4)
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    Superoxide dismutase [Cu-Zn] (SOD1)
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    T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4)
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    Tenascin (TNC)
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    Tenascin-X (TNXB)
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    Thrombospondin-4 (THBS4)
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    Thyroxine-binding globulin (SERPINA7)
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    Transcobalamin-2 (TCN2)
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    Transforming growth factor beta receptor type 3 (TGFBR3)
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    Transforming growth factor-beta-induced protein ig-h3 (TGFBI)
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    Trypsin-2 (PRSS2)
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    Tyrosine-protein kinase receptor Tie-1 (TIE1)
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    Uromodulin (UMOD)
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    Vascular cell adhesion protein 1 (VCAM1)
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    Vasorin (VASN)
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    Vitamin K-dependent protein C (PROC)
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