Proteogenomic strategies to advance drug development and precision medicine

Proteogenomic strategies to advance drug development and precision medicine

Speakers:  Professor Ulf Gyllensten (Uppsala University) & Dr. Anders Mälarstig (Pfizer Sweden)

During the webinar, the speakers:

  • Discussed how covariates (genetic, environmental, and clinical) can affect the levels of potential biomarkers
  • Explored the use of covariate modeling to establish personally normalized plasma protein profiles (PNPPP) to reduce non-disease-related variation and maximize clinical potential
  • Described how protein quantitative trait loci (pQTLs) can provide insights into disease biology and improve the efficiency of drug development


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