Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A)

Links to databases

 

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 0.95
    • LLOQ (pg/mL)
    • 3.81
    • ULOQ (pg/mL)
    • 31250
    • Hook (pg/mL)
    • 31250
    • Range (logs)
    • 3.9

Calibrator curve for validation data (generated in multiplex)

Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 11%
    • Between run precision Coefficient of Variation (CV)
    • 11%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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