Tissue factor (TF)

Links to databases

 

Tissue factor (TF) is the cell surface receptor for the serine protease factor VIIa. The best known function of TF is its role in blood coagulation. The complex of TF with factor VIIa catalyzes the conversion of the inactive protease factor X into the active protease factor Xa. TF is expressed by cells which are normally not exposed to flowing blood such as smooth muscle cells and cells surrounding blood vessels (e.g. fibroblasts). This can change when the blood vessel is damaged by physical injury or rupture of atherosclerotic plaques.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 0.24
    • LLOQ (pg/mL)
    • 0.24
    • ULOQ (pg/mL)
    • 31250
    • Hook (pg/mL)
    • 125000
    • Range (logs)
    • 5.1

Calibrator curve for validation data (generated in multiplex)

Tissue factor (TF)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 8%
    • Between run precision Coefficient of Variation (CV)
    • 13%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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