Interleukin-1 receptor-like 2 (IL1RL2)

Links to databases

 

IL1RL2 is a receptor for interleukin-36, and a member of the interleukin 1 receptor family. After binding to interleukin-36 associates with the co-receptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other similar pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system.

Sample type

Analytical Measuring Range

Please note: the technical data reported below refers to the measured value in the in vitro validation assays. The calibrator curve below shows the performance of the assay with the estimated sensitivity and dynamic range parameters indicated. These curves are generated during the assay validation process using recombinant antigens. Please note that when analyzing biological samples the data generated will be given in the form of relative quantification (NPX values) and cannot be converted to absolute protein concentrations. For more info about NPX measurements, please visit our FAQ page (https://www.olink.com/question/what-is-npx).

    • LOD (pg/mL)
    • 122.07
    • LLOQ (pg/mL)
    • 122.07
    • ULOQ (pg/mL)
    • 62500
    • Hook (pg/mL)
    • 125000
    • Range (logs)
    • 5.1

Calibrator curve for validation data (generated in multiplex)

Interleukin-1 receptor-like 2 (IL1RL2)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 10%
    • Between run precision Coefficient of Variation (CV)
    • 14%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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