Lectin-like oxidized LDL receptor 1 (LOX-1)

Links to databases

 

Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. LOX-1 is a protein that in humans is encoded by the OLR1 gene which has been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 0.95
    • LLOQ (pg/mL)
    • 0.95
    • ULOQ (pg/mL)
    • 15625
    • Hook (pg/mL)
    • 15625
    • Range (logs)
    • 4.2

Calibrator curve for validation data (generated in multiplex)

Lectin-like oxidized LDL receptor 1 (LOX-1)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 9%
    • Between run precision Coefficient of Variation (CV)
    • 11%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

View all CVD II panel biomarkers >

View all biomarkers >