Interleukin-18 (IL-18)

Links to databases

 

IL-18 is a pro-inflammatory cytokine that in combination with IL-12 induces cell-mediated immunity in the presence of microbial infection, which leads to the release of IFN-gamma. IL-18 can also induce severe inflammatory reactions and it has been described to be involved in several inflammation-related diseases such as Hashimoto?s thyroiditis, Alzheimer?s disease, rheumatoid arthritis, lung injury, etc.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 0.48
    • LLOQ (pg/mL)
    • 0.48
    • ULOQ (pg/mL)
    • 62500
    • Hook (pg/mL)
    • 125000
    • Range (logs)
    • 5.1

Calibrator curve for validation data (generated in multiplex)

Interleukin-18 (IL-18)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 11%
    • Between run precision Coefficient of Variation (CV)
    • 11%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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