Polymeric immunoglobulin receptor (PIgR)

Links to databases

 

PlgR is a receptor that binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 122.07
    • LLOQ (pg/mL)
    • 244.14
    • ULOQ (pg/mL)
    • 1000000
    • Hook (pg/mL)
    • 1000000
    • Range (logs)
    • 3.6

Calibrator curve for validation data (generated in multiplex)

Polymeric immunoglobulin receptor (PIgR)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 3%
    • Between run precision Coefficient of Variation (CV)
    • 14%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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