Chymotrypsin C (CTRC)

Links to databases

 

CTRC (also known as Caldecrin) is a member of the peptidase S1 family of proteins. It regulates activation and degradation of trypsinogens and procarboxypeptidases,targeting specific cleavage sites within their zymogen precursors.Physiologically, CTRC reduces the levels of serum calcium. Suboptimal CTRC activity can predispose patients to pancreatitis, due to a reduction in normal protective trypsin-degrading functionality.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 3.81
    • LLOQ (pg/mL)
    • 3.81
    • ULOQ (pg/mL)
    • 31250
    • Hook (pg/mL)
    • 31250
    • Range (logs)
    • 3.9

Calibrator curve for validation data (generated in multiplex)

Chymotrypsin C (CTRC)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 10%
    • Between run precision Coefficient of Variation (CV)
    • 10%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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