Thrombomodulin TM

Links to databases

 

Thrombomodulin reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is mainly synthesized by vascular endothelial cells, and inhibits coagulation and fibrinolysis. Mutations in the THBD gene can cause inherited thrombophilia. The THBD gene polymorphisims are associated with human disease and thrombomodulin plays a role in thrombosis, stroke, arteriosclerosis, and cancer.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 7.63
    • LLOQ (pg/mL)
    • 7.63
    • ULOQ (pg/mL)
    • 125000
    • Hook (pg/mL)
    • 125000
    • Range (logs)
    • 4.2

Calibrator curve for validation data (generated in multiplex)

Thrombomodulin  TM

Precision

    • Within run precision Coefficient of Variation (CV)
    • 11%
    • Between run precision Coefficient of Variation (CV)
    • 10%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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