Heme oxygenase 1 (HO-1)

Links to databases


Heme oxygenase, an essential enzyme in heme catabolism. It cleaves the heme ring to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase. The protein exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 1.91
    • LLOQ (pg/mL)
    • 7.63
    • ULOQ (pg/mL)
    • 31250
    • Hook (pg/mL)
    • 125000
    • Range (logs)
    • 3.6

Calibrator curve for validation data (generated in multiplex)

Heme oxygenase 1 (HO-1)


    • Within run precision Coefficient of Variation (CV)
    • 8%
    • Between run precision Coefficient of Variation (CV)
    • 10%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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