Angiotensin-converting enzyme 2 (ACE2)

Links to databases

 

ACE2 is a carboxypeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin 1-9, or the conversion of angiotensin II to the vasodilator peptide angiotensin 1-7. It is expressed in a wide range of cell types, but notably in vascular endothelial cells of the heart and the kidneys. ACE2 is an important regulator of heart function and also serves as functional receptor for the spike glycoprotein of some coronaviruses, including SARS.

Sample type

Analytical Measuring Range

    • LOD (pg/mL)
    • 15.26
    • LLOQ (pg/mL)
    • 15.26
    • ULOQ (pg/mL)
    • 62500
    • Hook (pg/mL)
    • 1000000
    • Range (logs)
    • 3.6

Calibrator curve for validation data (generated in multiplex)

Angiotensin-converting enzyme 2 (ACE2)

Precision

    • Within run precision Coefficient of Variation (CV)
    • 8%
    • Between run precision Coefficient of Variation (CV)
    • 11%

Precision (repeatability) is calculated from linearized NPX values over LOD.

Biomarker Validation Data

Additional validation data, as well as a more detailed description of how the Olink panels are quality controlled can be found in our Data Validation documents. To download or to learn more go to the Data Validation page.

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