Olink publications - over 600 and growing rapidly

Here you will find the latest list of publications that have used Olink’s panels for protein biomarker discovery in the reported studies, or which have reviewed our technology. The publications are grouped according to year of publication, and sorted alphabetically by first author. Links are provided to the journal abstract page or  PubMed entry for each publication, or where applicable, a link to the open-access full text version of the paper. The main list details articles based on human studies, for those based on studies in non-human species, go directly to non-human study publications

Tip: To search for keywords of interest within the publication titles below, type Ctrl+F and enter your search term.

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Chronological list of publications

2021

AbdennadherM, Inati S, Soldatos A, et al. Seizure phenotype in CLN3 disease and its relation to other neurologic outcome measures. (2021) Journal of Inherited Metabolic Disease, DOI: 10.1002/jimd.12366
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Abyazi ML, Bell KA, Gyimesi G, et al. Convergence of cytokine dysregulation and antibody deficiency in common variable immunodeficiency with inflammatory complications. (2021) Journal of Allergy and Clinical Immunology, DOI: 10.1016/j.jaci.2021.06.008
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Alexeev E, Dowdell A, Henen M, et al. Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage. (2021) FASEB Journal, DOI: 10.1096/fj.202100027R
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Armstrong G-S, Frank J, McLouth C, et al. Commentary: Use of BACTRAC Proteomic Database-Uromodulin Protein Expression During Ischemic Stroke. (2021) Journal of Experimental Neurology, Vol 2(1).
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Arunachalam P, Scott M, Hagan T, et al. Systems vaccinology of the BNT162b2 mRNA vaccine in humans. (2021) Nature, DOI: 10.1038/s41586-021-03791-x
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Arvidsson M, Ahmed A, Bouzina H and Rådegran G. Plasma proteoglycan prolargin in diagnosis and differentiation of pulmonary arterial hypertension. (2021) ESC Heart Failure, DOI: 10.1002/ehf2.13184
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Babačić H, Eriksson B, and Pernemalm M. Plasma proteome alterations by MAPK inhibitors in BRAFV600-mutated metastatic cutaneous melanoma. (2021) Neoplasia, DOI: 10.1016/j.neo.2021.06.002
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Bakker O, Ramírez-Sánchez A, Borek Z, et al. Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells. (2021) Scientific Reports, DOI: 10.1038/s41598-021-86612-5
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Barron-Millar B, Ogle L, Mells G, et al. The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis. (2021) Hepatology, DOI: 10.1002/hep.32011
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Bergemalm D, Andersson E, Hultdin J, et al.  Systemic Inflammation in Preclinical Ulcerative Colitis. (2021) Gastroenterology, DOI: 10.1053/j.gastro.2021.07.026
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Bhardwaj M, Terzer T, Schrotz-King P, Brenner H. Comparison of Proteomic Technologies for Blood-Based Detection of Colorectal Cancer. (2021) International  Journal of Molecular Sciences, DOI: 10.3390/ijms22031189
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Bouwens E, Schuurman A-S, Akkerhuis K, et al. Associations of serially measured PCSK9, LDLR and MPO with clinical outcomes in heart failure. (2021) Future Medicine, DOI: 10.2217/bmm-2020-0585
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Broberg K, Svensson J, Grahn K, et al. Evaluation of 92 cardiovascular proteins in dried blood spots collected under field‐conditions. (2021) BioEssays, DOI: 10.1002/bies.202000299
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Bryl-Górecka P, James K, Torngren K et al. Microvesicles in plasma reflect coronary flow reserve in patients with cardiovascular disease. (2021) Heart and Circulatory Physiology, DOI: 10.1152/ajpheart.00869.2020
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Buitrago-Molina L, Dywicki J, Noyan F, et al. Splenectomy Prior to Experimental Induction of Autoimmune Hepatitis Promotes More Severe Hepatic Inflammation. (2021) Biomedicines, DOI: 10.3390/biomedicines9010058
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Buitrago-Molina L, Pietrek J, Noyan F, et al. Treg-specific IL-2 therapy can reestablish intrahepatic immune regulation in autoimmune hepatitis. (2021) Journal of Autoimmunity, DOI: 10.1016/j.jaut.2020.102591
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Bäckryd E, Themistocleous A, Larsson A, et al. Hepatocyte growth factor, colony-stimulating factor 1, CD40, and 11 other inflammation-related proteins are associated with pain in diabetic neuropathy. (2021) Pain, DOI: 10.1097/j.pain.0000000000002451
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C, Gorreja F, Forsskåhl S, et al. REM-1+ Macrophages Define a Pathogenic Cell Subset in the Intestine of Crohn’s Disease Patients. (2021) Journal of Crohn’s and Colitis, DOI: /10.1093/ecco-jcc/jjab022
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Camargo MC, Song M, Ito H, et al Associations of circulating mediators of inflammation, cell regulation and immune response with esophageal squamous cell carcinoma. (2021) Journal of Cancer Research and Clinical Oncology, DOI: 10.1007/s00432-021-03687-3
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Camargo MC, Song M, Sawada N, et al. Prediagnostic circulating inflammation-related biomarkers and gastric cancer: A case-cohort study in Japan. (2021) Cytokine, DOI: 10.1016/j.cyto.2021.155558
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Cauwenberghs N, Sabovčik F, Magnus A, et al. Proteomic profiling for detection of early-stage heart failure in the community. (2021) ESC Heart Failure, DOI: 10.1002/ehf2.13375
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Chen M, Ren A, Prassas I, et al. Plasma Protein Profiling by Proximity Extension Assay Technology Reveals Novel Biomarkers of Traumatic Brain Injury—A Pilot Study. (2021) The Journal of Applied Laboratory Medicine, DOI: 10.1093/jalm/jfab004
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Chorell E, Olsson T, Jansson J-H and Wennberg P. Lysophospholipids as Predictive Markers of ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI). (2021) Metabolites, DOI: 10.3390/metabo11010025
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Chua W, Law J, Cardoso R, et al. Quantification of fibroblast growth factor 23 and N-terminal pro-B-type natriuretic peptide to identify patients with atrial fibrillation using a high-throughput platform: A validation study. (2021) PLOS Medicine, DOI: 10.1371/journal.pmed.1003405
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Cotungo N, Ruggiero A, Bonfante F, et al. Virological and immunological features of SARS-CoV-2-infected children who develop neutralizing antibodies. (2021) Cell reports, DOI: 10.1016/j.celrep.2021.108852
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Cuff S, Merola J, Twohih J, et al. Toll-like receptor linked cytokine profiles in cerebrospinal fluid discriminate neurological infection from sterile inflammation. (2021) Brain Communications, DOI: 10.1093/braincomms/fcaa218
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Dagnino S, Bodinier B, Guida F, et al. Prospective Identification of Elevated Circulating CDCP1 in Patients Years before Onset of Lung Cancer. (2021) Cancer Research, DOI: 10.1158/0008-5472.CAN-20-3454
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Danielsson H, Tebani A, Zhong W, et al. Blood protein profiles related to preterm birth and retinopathy of prematurity. (2021) Pediatric Research, DOI: 10.1038/s41390-021-01528-0
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da Silva Antunes R, Soldevila F, Pomaznoj M, et al. A system-view of Bordetella pertussis booster vaccine responses in adults primed with whole-cell versus acellular vaccine in infancy. (2021) JCI Insight, DOI: 10.1172/jci.insight.141023
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David P, Hansen F, Bhat A, and Weber G. An overview of proteomic methods for the study of ‘cytokine storms’. (2021) Expert Review of Proteomics, DOI: 10.1080/14789450.2021.1911652
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Davidson L, van den Reek J, Bruno M, et al. Risk of candidiasis associated with interleukin-17 inhibitors: A real-world observational study of multiple independent sources. (2021) The Lancet Regional Health – Europe, DOI: 10.1016/j.lanepe.2021.100266
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Davison B, Senger S, Sama I, et al. Is Acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF. (2021) European Journal of Heart Failure, DOI: 10.1002/ejhf.2077
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de Jesús-Gil C, Sans-de San Nicolàs L, Ruiz-Romeu E, et al.  Interplay between Humoral and CLA+ T Cell Response against Candida albicans in Psoriasis. (2021) International Journal of Molecular Sciences, DPO:10.3390/ijms22041519
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Drake I, Hindy G, Almgren P, et al.  Methodological considerations for identifying multiple plasma proteins associated with all-cause mortality in a population-based prospective cohort. (2021) Scientific Reports, DOI: 10.1038/s41598-021-85991-z
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Drake I, Fryk E, Strindberg L, et al. The role of circulating galectin-1 in type 2 diabetes and chronic kidney disease: evidence from cross-sectional, longitudinal and Mendelian randomisation analyses. (2021) Diabetologia, DOI: 0.1007/s00125-021-05594-1
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Drzeniek NM, Mazzocchi A, Schlickeiser S, et al. Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells. (2021) Biofabrication, DOI: 10.1088/1758-5090/ac0a32
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Dubin C, Glickman J, Del Duca E, et al. Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. (2021) Journal of the American Academy of Dermatology
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Eggers K, Lindhagen L, Baron T, et al. Sex-differences in circulating biomarkers during acute myocardial infarction: An analysis from the SWEDEHEART registry. (2021) PLOS ONE, DOI: 10.1371/journal.pone.0249830
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Eggers KM, Lindhagen L, Lindhagen L, et al. Predicting outcome in acute myocardial infarction: an analysis investigating 175 circulating biomarkers. (2021) European Heart Journal Acute Cardiovascular Care, DOI: 10.1093/ehjacc/zuaa014
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Falck-Jones S, Vangeti S, Yu M, et al. Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity. (2021) Journal of Clinical Investigation, DOI: 10.1172/JCI144734
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Faxen U, Venkateshvaran A, Shah S, et al. Generalizability of HFA-PEFF and H2FPEF Diagnostic Algorithms and Associations With Heart Failure Indices and Proteomic Biomarkers: Insights From PROMIS-HFpEF. (2021) Journal of Cardiac failure, DOI: 10.1016/j.cardfail.2021.02.005
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Fearghail F, Behan P, Engström N, and Scheers N. A LCMS Metabolomic Workflow to Investigate Metabolic Patterns in Human Intestinal Cells Exposed to Hydrolyzed Crab Waste Materials. (2021) Frontiers in Bioengineering and Biotechnology, DOI: 10.3389/fbioe.2021.629083
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Fellström B, Helmersson-Karlqvist J, Lind L, et al. Albumin Urinary Excretion Is Associated with Increased Levels of Urinary Chemokines, Cytokines, and Growth Factors Levels in Humans. (2021) Biomolecules, DOI: 10.3390/biom11030396
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Filbin M, Mehta A, Schneider A, et al. Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions. (2021) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2021.100287
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Forrer A, Felix Schoenrath F, Torzewski M, et al. Novel Blood Biomarkers for a Diagnostic Workup of Acute Aortic Dissection. (2021) Diagnostics, DOI: 10.3390/diagnostics11040615
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Fourman L, Stanley T, Billingsley J, et al. Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach. (2021) Scientific Reports, DOI: 10.1038/s41598-021-89966-y
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Franzén B, Viktorsson K, Kamali C, et al. Multiplex immune protein profiling of fine-needle aspirates from patients with non-small-cell lung cancer reveals signatures associated with PD-L1 expression and tumor stage. (2021) Molecular Oncology, DOI: 10.1002/1878-0261.12952
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Gisby J, Clarke C, Medjeral-Thomas N, et al. Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death. (2021) eLife, DOI: 10.7554/eLife.64827
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Glickman J, Dubin C, Dahabreh D, et al. An integrated scalp and blood biomarker approach suggests the systemic nature of alopecia areata. (2021) Allergy, DOI: 10.1111/all.14814
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Gradin A, Andersson H, Luther T, et al.  Urinary cytokines correlate with acute kidney injury in critically ill COVID-19 patients. (2021) Cytokine, DOI: 10.1016/j.cyto.2021.155589
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Grasberger H, Magis A, Sheng e, et al. DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk. (2021) Journal of Clinical Investigation, DOI: 10.1172/JCI141676
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Gülen T, Teufelberger A, Ekoff M, et al. Distinct plasma biomarkers confirm the diagnosis of mastocytosis and identify increased risk of anaphylaxis. (2021) Journal of Allergy and Clinical Immunology, DOI: 10.1016/j.jaci.2021.02.023
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Haq Z, Yang D, Psaras C, and Stewart J. Sex-Based Analysis of Potential Inflammation-Related Protein Biomarkers in the Aqueous Humor of Patients With Diabetes Mellitus. (2021) Translational Vision Science & Technology, DOI: 10.1167/tvst.10.3.12
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He H, Olesen C, Pavel A, et al. Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers (2021) Frontiers in Immunology, DOI: 10.3389/fimmu.2020.01768
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Herder C, Maalmi H, Strassburger K, et al. Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset Diabetes. (2021) Diabetes, DOI: 10.2337/db20-1054
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Himmelsbach R, Landerer A, Hipp J, et al. Immunological effects of hybrid minimally invasive versus conventional open pancreatoduodenectomy – A single center cohort study. (2021) Pancreatology, DOI: 0.1016/j.pan.2021.03.014
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Hofstee H, Heider A, Häckel S, et al. In Vitro 3D Staphylococcus aureus Abscess Communities Induce Bone Marrow Cells to Expand into Myeloid-Derived Suppressor Cells. (2021) Pathogens, DOI: 10.3390/pathogens10111446
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Holst CB, Christensen IJ, Vitting-Seerup K, et al.  Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma.. (2021) Neurooncology Advances, DOI: 10.1093/noajnl/vdab072
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Hussain A, Tang O, Sun C, et al. Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (From the Atherosclerosis Risk in Communities Study). (2021) American Journal of Cardiology, DOI: 10.1016/j.amjcard.2021.01.017
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Ihara K, Skipien J, KrolewskiB, et al. A profile of multiple circulating TNF receptors associated with early progressive renal decline in Type 1 Diabetes; similar to profiles in autoimmune disorders (2021) Kidney International, DOI: 10.1016/j.kint.2020.07.007
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Isung J, Granqvist M, Trepci A, et al. Differential effects on blood and cerebrospinal fluid immune protein markers and kynurenine pathway metabolites from aerobic physical exercise in healthy subjects. (2021) Scientific Reports, DOI: 0.1038/s41598-021-81306-4
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Jackson S, Van De Wyngard V, Pfeiffer R, et al. Inflammatory profiles in Chilean Mapuche and non-Mapuche women with gallstones at risk of developing gallbladder cancer. (2021) Scientific Reports, DOI: 0.1038/s41598-021-83300-2
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Janssen N, Grondman I, de Nooijer A, et al. Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19. (2021) Journal of Infectious Diseases, DOI: 10.1093/infdis/jiab065
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Jenner J, Ilami A, Petrini J, et al. Pre- and postoperative left atrial and ventricular volumetric and deformation analyses in severe aortic regurgitation. (2021) Cardiovascular Ultrasound, DOI: 10.1186/s12947-021-00243-4
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Jiang Y, Zhou X, Ip FC, et al. Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer’s disease screening and staging. (2021) Alzheimers & Dementia, DOI: 10.1002/alz.12369
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Jujic A, Matthes F, Van Herie L, et al. Plasma S1P (Sphingosine-1-Phosphate) Links to Hypertension and Biomarkers of Inflammation and Cardiovascular Disease: Findings From a Translational Investigation. (2021) Hypertension, DOI: 10.1161/HYPERTENSIONAHA.120.17379
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Just D, Rasmusson A, Nilsson P, et al. Autoantibodies against the C-terminus of Lipopolysaccharide binding protein are elevated in young adults with psychiatric disease. (2021) Psychoneuroendocrinology, DOI: 10.1016/j.psyneuen.2021.105162
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Kaiser H, Wang X, Kvist-Hansen A, et al. Biomarkers of subclinical atherosclerosis in patients with psoriasis. (2021) Scientific Rports, DOI: 10.1038/s41598-021-00999-9.
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Katz D, Tahir U, Bick A, et al. Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights into Cardiovascular Disease. (2021) Circulation, DOI: 10.1161/CIRCULATIONAHA.121.055117
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Kerzeli I, Lord M, Doroszko M, et al. Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations. (2021) PLOS One, DOI: 10.1371/journal.pone.0253178
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Khera T, Du Y, Todt D, et al. Long-lasting Imprint in the Soluble Inflammatory Milieu despite Early Treatment of Acute Symptomatic Hepatitis C. (2021) Journal of Infectious Diseases, DOI: 10.1093/infdis/jiab048
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Kim D, Park G, Huuhtanen J, et al. STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation. (2021) Leukemia, DOI: 10.1038/s41375-021-01296-0
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Klevebro S, Björkander S, Ekström S, et al. Inflammation-related plasma protein levels and association with adiposity measurements in young adults. (2021) Scientific Reports, DOI: 0.1038/s41598-021-90843-x
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Klinkvort Kempel M, Winding TN, Lynggaard V, et al. Traditional and novel cardiometabolic risk markers across strata of body mass index in young adults. (2021) Obesity Science & Practice, DOI: 10.1002/osp4.528
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Kraen M, Frantz S, Nihlén U, et al. Fibroblast growth factor 23 is an independent marker of COPD and is associated with impairment of pulmonary function and diffusing capacity. (2021) Respiratory Medicine, DOI: 10.1016/j.rmed.2021.106404
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Kragstrup T, Singh H, Grundberg I, et al. Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients.. (2021) LOS ONE, DOI: 10.1371/journal.pone.0252799
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Kvedaraite E, Hertwig L, Sinha I, et al. Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity. (2021) PNAS, DOI: 10.1073/pnas.2018587118
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Lekva T, Jacobsen D, Sugulle M, et al. Circulating HLA-G and its association with cardiovascular markers in pregnancy. (2021) Journal of Reproductive Immunology, DOI: 10.1016/j.jri.2021.103331
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Levine J, Oleaga C. Eren M, et al. Role of PAI-1 in hepatic steatosis and dyslipidemia. (2021) Scientific Reports, DOI: 10.1038/s41598-020-79948-x
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Levy B, Fritz C, Piona C, et al. Hemodynamic and anti-inflammatory effects of early esmolol use in hyperkinetic septic shock: a pilot study. (2021) Critical Care, DOI: 10.1186/s13054-020-03445-w
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Lind L, Gigante B, Borné Y, et al. Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes. (2021) Arteriosclerosis, Thrombosis, and Vascular Biology, DOI: 10.1161/ATVBAHA.120.315597
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Lind L, Sundström J and Ärnlöv J Proteins associated with incident metabolic syndrome in population-based cohorts. (2021) Diabetology and Metabolic Syndrome, DOI: 10.1186/s13098-021-00752-2
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Lindau R, Vondra S, Spreckels J, et al. Decidual stromal cells support tolerance at the human foetal-maternal interface by inducing regulatory M2 macrophages and regulatory T-cells. (2021) Journal of Reproductive Immunology, DOI: 10.1016/j.jri.2021.103330
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Lindgaard S, Sztupinszki Z, Maag E, et al. Circulating Protein Biomarkers for Use in Pancreatic Ductal Adenocarcinoma Identification. (2021) Clinical Cancer Research, DOI: 10.1158/1078-0432.CCR-20-4215
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Liu S, Garcia-Marques F, Zhang C, et al. Discovery of CASP8 as a potential biomarker for high-risk prostate cancer through a high-multiplex immunoassay. (2021) Scientific Reports, DOI: 10.1038/s41598-021-87155-5
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Livanos A, Jha D, Cossarni F, et al. Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms. (2021) Gastroenterology, DOI: 10.1053/j.gastro.2021.02.056
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Majewski S, Zhou XW, Miłkowska-Dymanowska J, et al. Proteomic profiling of peripheral blood and bronchoalveolar lavage fluid in interstitial lung diseases: An explorative study. (2021) ERJ Open Research, DOI: 10.1183/23120541.00489-2020
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Maglinger B, Sands M, Frank J,  et al. Intracranial VCAM1 at time of mechanical thrombectomy predicts ischemic stroke severity. (2021) Journal of Neuroinflammation, DOI: 10.1186/s12974-021-02157-4
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Maucourant C, Filipovic I, Ponzetta A, et al. Natural killer cell immunotypes related to COVID-19 disease severity. (2021) Science Immunology, DOI: 10.1126/sciimmunol.abd6832
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McKay T, Rhee J, Colon K, et al. Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery. (2021) Journal of Cardiothoracic and Vascular Anesthesia, DOI: 10.1053/j.jvca.2021.05.002
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Md Dom ZI, Pipino C, Krolewski B, et al. Effect of TNFα stimulation on expression of kidney risk inflammatory proteins in human umbilical vein endothelial cells cultured in hyperglycemia. (2021) Scientific Reports, DOI: 10.1038/s41598-021-90496-w
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Molendijk J and Parker B. Proteome-wide Systems Genetics to Identify Functional Regulators of Complex Traits. (2021) Cell Systems, DOI: 10.1016/j.cels.2020.10.005
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Monjazeb A,  Giobbie-Hurder A, Lako A, et al. A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-Dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer. (2021) Clinical Cancer Research, DOI: 0.1158/1078-0432.CCR-20-4632
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Mulder T, Peña-Pérez L, Berglöf A, et al. Ibrutinib Has Time-dependent On- and Off-target Effects on Plasma Biomarkers and Immune Cells in Chronic Lymphocytic Leukemia. (2021) Hemasphere, DOI: 10.1097/HS9.0000000000000564
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Møller PL, Rohde PD, Winther S, et al. Sortilin as a Biomarker for Cardiovascular Disease Revisited. (2021) Frontiers in Cardiovascular Medicine, DOI: 10.3389/fcvm.2021.652584
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Nabais, M.F., Laws, S.M., Lin, T. et al. Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. (2021) Genome Biology, DOI: 10.1186/s13059-021-02275-5
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Navrazhina K, Renert-Yuval Y, Frew J, et al. Large-scale serum analysis identifies unique systemic biomarkers in psoriasis and hidradenitis suppurativa. (2021) British Journal of Dermatology, DOI: 10.1111/bjd.20642
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Pan J, Borné Y, Orho-Melander M,  et al. The associations between red cell distribution width and plasma proteins in a general population. . (2021) Clinical Proteomics, DOI: 0.1186/s12014-021-09319-9
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Patel H, Ashton N, Dobson R, et al. Proteomic blood profiling in mild, severe and critical COVID-19 patients. (2021) Scientific Reports, DOI: 10.1038/s41598-021-85877-0
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Patel R, Freed B, Beussink-Nelson L, et al. Associations of Cardiac Mechanics With Exercise Capacity: The Multi-Ethnic Study of Atherosclerosis. (2021) Journal of the American College of Cardiology, DOI: 10.1016/j.jacc.2021.04.082
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Patel R, Lam C, Svedlund S, et al. Disproportionate left atrial myopathy in heart failure with preserved ejection fraction among participants of the PROMIS-HFpEF study. (2021) Scientific Reports, DOI: 10.1038/s41598-021-84133-9
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Pavlović N, Kopsida M,  Gerwins P and Heindryckx, F. Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment. (2021) Life Sciences, DOI: 10.1016/j.lfs.2021.119612
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Pettersson-Pablo P, Nilsson T, Breimer L, et al. IGFBP-1 and IGFBP-2 are associated with a decreased pulse-wave velocity in young, healthy adults. (2021) BMC Cardiovascular Disorders, DOI: 10.1186/s12872-021-01914-w
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Ponce de León-Rodríguez M, Linseisen J, Peters A, et al. Novel associations between inflammation-related proteins and adiposity: a targeted proteomics approach across four population-based studies. (2021) Translational Research, DOI: 10.1016/j.trsl.2021.11.004
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Reimegård J, Tarbier M, Danielsson M, et al. A combined approach for single-cell mRNA and intracellular protein expression analysis. (2021) Communications Biology, DOI: 10.1038/s42003-021-02142-w
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Remsik J, Wilcox J, Babady NE, et al. Inflammatory leptomeningeal cytokines mediate COVID-19 neurologic symptoms in cancer patients. (2021) Cancer Cell, DOI: 10.1016/j.ccell.2021.01.007
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Renert-Yuval Y, Thyssen J, Bissonnette R, et al. Biomarkers in atopic dermatitis—a review on behalf of the International Eczema Council. (2021) Journal of Allergy and Clinical Immunology, DOI: 10.1016/j.jaci.2021.01.013
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Resl M, Heinzl M, Klammer C, et al. Storm of Cardiovascular Markers After LPS Administration in Human Volunteers. (2021) Journal of Cardiovascular Translational Research , DOI: 0.1007/s12265-021-10109-9
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Reyes M, Filbin MR, Bhattacharyya RP, et al. Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro.. (2021) Science Translational Medicine, DOI: 10.1126/scitranslmed.abe9599
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Rinaldi A, Korsfeldt A, Ward S, et al. Electrical impedance spectroscopy for the characterization of skin barrier in atopic dermatitis. (2021) Allergy, DOI: 10.1111/all.14842
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Rittmann M, Hussung S, Braun L, et al.  Plasma biomarkers for prediction of early tumor recurrence after resection of pancreatic ductal adenocarcinoma. (2021) Scientific Reports, DOI: 10.1038/s41598-021-86779-x
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Robbins JM, Peterson B, Schranner D, et al. Human plasma proteomic profiles indicative of cardiorespiratory fitness. (2021) Nature Metabolism, DOI: 10.1038/s42255-021-00400-z
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Rozeman E, Hoefsmit E, Reijers I, et al. Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma. (2021) Nature Medicine, DOI: 10.1038/s41591-020-01211-7
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Shen Q, Polomb K, Williams C, Souza de Oliveira FM, Guergova-Kuras M, Lisacek F, Karlsson N, Roviello F and Kamali-Moghaddama M. A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer. (2019) EBioMedicine, 10.1016/j.ebiom.2019.05.044
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Säleby J, Bouzina H, Ahmed S, Lundgren J and Rådegran G. Plasma receptor tyrosine kinase RET in pulmonary arterial hypertension diagnosis and differentiation. (2019) ERJ Open Research,  DOI: 10.1183/23120541.00037-2019
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Tebroke J, Lieverse J, Säfholm J, Schulte G, Nilsson G and Rönnberg E. Wnt-3a Induces Cytokine Release in Human Mast Cells. (2019) Cells, DOI: 10.3390/cells8111372
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Tomalin L, Kim J, Correa da Rosa J, Lee J, Fitz L, Berstein G, Valdez H, Wolk R, Krueger J and Suárez-Fariñas M. Early quantification of systemic inflammatory-proteins predicts long-term treatment response to Tofacitinib and Etanercept: Psoriasis response predictions using blood. (2019) Journal of Investigative Dermatology, DOI: 10.1016/j.jid.2019.09.023
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van den Berg V, Bouwens E, Umans V, de Maat M, Manintveld O, Caliskan K, Constantinescu A, Caliskan K, Constantinescu A, Mouthaan H, Cornel J-H, Baart S, Akkerhuis M, Boersma E and Kardys I. Longitudinally Measured Fibrinolysis Factors are Strong Predictors of Clinical Outcome in Patients with Chronic Heart Failure: The Bio-SHiFT Study. (2019) Thrombosis and Haemostasis, DOI: 10.1055/s-0039-1696973
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van der Zwan M, Hesselink D, Clahsen-van Groningen M and Baan C. Targeted proteomic analysis detects acute T cell-mediated kidney allograft rejection in belatacept-treated patients. (2019) Therapeutic Drug Monitoring, doi: 10.1097/FTD.0000000000000587
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Wang H, Davison M, Wang K, Xia T-H, Kramer M, Call K, Luo J, Wu X, Zuccarino R, Bacon C, Bai Y, Moran J, Gutmann L, Feely S, Grider T, Rossor A, Reilly M, Svaren J and Shy M. Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A. (2019) Annals of Clinical & Translational Neurology, DOI: 10.1002/acn3.50965
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Whelan C, Mattsson N, Nagle M, Vijayaraghavan S, Hyde C, Janelidze S, Stomrud E, Lee J, Fitz L, Samad T, Ramaswamy G, Margolin R, Mälarstig A and Hansson O. Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer’s disease. (2019) Acta Neuropathologica Communications, DOI: 10.1186/s40478-019-0795-2
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Wiberg A, Olsson-Strömberg U, Herman S, Kultima K and Burman J. Profound but Transient Changes in the Inflammatory Milieu of the Blood During Autologous Hematopoietic Stem Cell Transplantation. (2019) Biology of Blood and Marrow Transplantation, DOI: 10.1016/j.bbmt.2019.09.010
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Wierenga A, Cao J, Mouthaan H, van Weeghel C, Verdijk R, van Duinen S, Kroes W, Dogrusöz M, Marinkovic M, van der Burg S, Luyten G and Jager M. Aqueous Humor Biomarkers Identify Three Prognostic Groups in Uveal Melanoma. (2019) Investigative Ophthalmology & Visual Science, DOI: 10.1167/iovs.19-28309
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Wu P-H, Chiu Y-W, Zou H-B, Lee S-C, Lin Y-T, Tsai Y-T, Kuo M-C and Hwang S-J. Exploring the Benefit of 2-Methylbutyric Acid in Patients Undergoing Hemodialysis Using a Cardiovascular Proteomics Approach. (2019) Nutrition, DOI: 10.3390/nu11123033
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Zamaratskaia G, Omar NAM, Brunius C, Hallmans G, Johansson J-E, Andersson S-O, Larsson A, Åman P. and Landberg R. Consumption of whole grain/bran rye instead of refined wheat decrease concentrations of TNF-R2, e-selectin, and endostatin in an exploratory study in men with prostate cancer. (2019) Clinical Nutrition, doi.org/10.1016/j.clnu.2019.01.007
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Zheng J, Maerz W, Gergei I et. al. Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures. (2019) Journal of Bone and Mineral Research, DOI: 10.1002/jbmr.3803
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Abrahamsson A, Rzepecka A and Dabrosin C. Equal Pro-inflammatory Profiles of CCLs, CXCLs, and Matrix Metalloproteinases in the Extracellular Microenvironment In Vivo in Human Dense Breast Tissue and Breast Cancer. (2018) Frontiers in Immunology, doi: 10.3389/fimmu.2017.01994
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Al-Talabany S, Mordi I, Houston G, Colhoun H, Weir-McCall J, Matthew S, Looker H, Levin D, Belch J, Dove F, Khan F and Lang C. Epicardial adipose tissue is related to arterial stiffness and inflammation in patients with cardiovascular disease and type 2 diabetes. (2018) BMC Cardiovascular Disorders, doi.org/10.1186/s12872-018-0770-z
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Aqrawi L, Ivanchenko M, Björk A, Ramírez Sepúlveda J, Imgenberg-Kreuz J, Kvarnström M, Haselmayer P, Jensen J, Nordmark G, Chemin K, Skarstein G and Wahren-Herlenius M. Diminished CXCR5 expression in peripheral blood of patients with Sjögren’s syndrome may relate to both genotype and salivary gland homing. (2018) Clinical & Experimental  Immunology, doi: 10.1111/cei.13118
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Arrigo M, Vodovar N,Von Moos S, Masson E, Segerer S, Cippà P and Mebazaa A. High accuracy of proximity extension assay technology for the quantification of plasma brain natriuretic peptide. (2018) Journal of  Clinical Laboratory Analysis, doi.org/10.1002/jcla.22574
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Bao X, Borné Y, Faqir Muhammad I, Nilsson J, Lind L, Melander O, Niu K, Orho-Melander M and Engström G. Growth differentiation factor 15 is positively associated with incidence of diabetes mellitus: the Malmö Diet and Cancer–Cardiovascular Cohort (2018)  Diabetologia, DOI/10.1007/s00125-018-4751-7
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Barriuso J, Custodio A, Afonso R, Alonso V, Astudillo A, Capdevila J, Carbonero R, Grande E, Jimenez-Fonseca P, Marazuela M, Rodríguez-Antona C and Aller Y. Prognostic and predictive biomarkers for somatostatin analogs, peptide receptor radionuclide therapy and serotonin pathway targets in neuroendocrine tumours. (2018) Cancer Treatment Reviews, doi.org/10.1016/j.ctrv.2018.09.00
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Barwari T, Eminaga S, Mayr U, Lu R, Armstrong P, Chan M, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley S, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah A, Ghevaert C, Warner T, Fernández-Hernando C, Suárez Y and Mayr M. Inhibition of profibrotic microRNA-21 affects platelets and their releasate. (2018) Journal of Clinical Investigation, doi.org/10.1172/jci.insight.123335.
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Berntsson J, Smith G, Johnson L, Söderholm M, Borné Y, Melander O, Orho-Melander M, Nilsson J and Engström G. Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke. (2018) Heart, doi:10.1136/heartjnl-2018-313684
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Bhandage A, Jin Z, Korol S, Shenb Q, Pe Y, Deng Q, Espes D, Carlsson P-O, Kamali-Moghaddamb M and Birnir B. GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes. (2018) EBioMedicine, doi.org/10.1016/j.ebiom.2018.03.019
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Birgirsson H, Tsimogiannis K, Freyhult E and Kamali-Moghaddam M. Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer. (2018) Translational Oncology, doi:/10.1016/j.tranon.2018.05.012
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Bouzina H and Rådergran G. Low plasma stem cell factor combined with high transforming growth factor-α identifies high-risk patients in pulmonary arterial hypertension. (2018) ERJ Open Research, DOI: 10.1183/23120541.00035-2018.
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Brankovic M, Akkerhuis K, Mouthaan H, Brugts J, Manintveld O, van Ramshorst J, Germans T, Umans V, Boersma E and Kardys I. Cardiometabolic biomarkers and their temporal patterns predict poor outcome in chronic heart failure (Bio-SHiFT study). (2018) The Journal of Clinical Endocrinology & Metabolism, DOI: 10.1210/jc.2018-01241
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Brankovic M, Akkerhuis K, Mouthaan H, Constantinescu A, Caliskan K, van Ramshorst J, Germans T, Umans V and Kardys I. Utility of temporal profiles of new cardio-renal and pulmonary candidate biomarkers in chronic heart failure. (2018) International Journal of Cardiology, DOI: 10.1016/j.ijcard.2018.08.001
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Bränn E, Fransson E, White R, Papadopoulos F, Edvinsson Å, Kamali‐Moghaddam M, Cunningham J, Sundström‐Poromaa I and Skalkidou  A. Inflammatory markers in women with postpartum depressive symptoms (2018) Journal of Neuroscience Research, doi.org/10.1002/jnr.24312
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Cañadas-Garre M, Anderson K, McGoldrick J, Maxwell A and McKnight A. Proteomic and metabolomic approaches in the search for biomarkers in chronic kidney disease. (2018) Journal of Proteomics, doi:10.1016/j.jprot.2018.09.020
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Carlyle B, Trombetta B and Arnold S. Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias (2018) Proteomes, doi:10.3390/proteomes6030032
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Csösz E, Tóth N, Deák, E, Csutak A and Tözsér J. Wound-Healing Markers Revealed by Proximity Extension Assay in Tears of Patients following Glaucoma Surgery. (2018) Int. J. Mol. Sci, doi:10.3390/ijms19124096
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Defilippi C, Lo J, Christenson R, Grundberg I, Stone L, Zanni M, Lee H and Grinspoon S. Novel mediators of statin effects on plaque in HIV: a proteomics approach. (2018) AIDS, doi.org/10.1097/QAD.0000000000001762
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Dencker M, Arvidsson D, Karlsson M, Wollmer P, Andersen L and Thorsson O. Galectin-3 levels relate in children to total body fat, abdominal fat, body fat distribution, and cardiac size (2018) European J. Paediatrics, doi: 10.1007/s00431-017-3079-5
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Dencker M, Gårdinger Y, Björgell O and Hlebowicz J. Effect of food intake on biomarkers for cardiovascular disease and inflammation analyzed with the Proseek Multiplex CVD II kit. (2018) Genetics and Molecular Research, DOI: 10.4238/gmr16039884
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Di Pietro V, Porto E, Ragusa M, Barbagallo C, Davies D, Forcione M, Logan A, Di Pietro C, Purrello M, Grey M, Hammond D, Sawlani V, Barbey A and Belli A. Salivary microRNAs: diagnostic markers of mild traumatic brain injury in contact-sport. (2018) Frontiers in Molecular Neuroscience, doi.org/10.3389/fnmol.2018.00290
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Edvinsson Å, Bränn E,  Hellgren C, Freyhult E, White R, Kamali-Moghaddam M, Olivier J, Bergquist J, Boström A, Schiöth H, Skalkidou A, Cunningham J and Sundström-Poroma  I. Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction. (2018) Psychoneuroendocrinology, doi: 10.1016/j.psyneuen.2017.02.027
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Enblad G, Karlsson H, Gammelgård G, Wenthe J, Lövgren T, Amini M, Wikstrom K, Essand M, Savoldo B, Hallböök H, Höglund M, Dotti G, Brenner M, Hagberg H and Loskog A. A Phase I/IIa Trial Using CD19-Targeted ThirdGeneration CAR T Cells for Lymphoma and Leukemia. (2018) Clinical Cancer Research, doi: 10.1158/1078-0432.CCR-18-0426
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Enroth S, Berggrund M, Lycke M, Lundberg M, Assarsson E, Olovsson M, Stålberg K, Sundfeldt K and Gyllensten U. A two-step strategy for identification of plasma protein biomarkers for endometrial and ovarian cancer. (2018) Clinical Proteomics, doi: 10.1186/s12014-018-9216-y
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Enroth S, Maturi, V, Berggrundi, M, Bosdotter Enroth S, Moustakas A, Johansson Å and Gyllensten U. Systemic and specific effects of antihypertensive and lipid-lowering medication on plasma protein biomarkers for cardiovascular diseases. (2018) Scientific Reports, DOI:10.1038/s41598-018-23860-y
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Feldreich T, Nowak C, Fall T, Carlsson A, Carrero J-J, Ripsweden J, Qureshi AR, Heimbürger O, Barany P, Stenvinke P, Vuilleumier N, Kalra P, Green D and Ärnlöv J. Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease. (2018) Journal of Nephrology, doi: 10.1007/s40620-018-0556-5
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Fernandez C, Rysä J, Almgren P, Nilsson J, Engström G, Orho‐Melander M, Ruskoaho H and Melander O. Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality. (2018) Journal of Internal Medicine, doi.org/10.1111/joim.12783
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Figarska S, Gustafsson S, Sundström J, Ärnlöv J, Mälarstig A, Elmståhl S, Fall T, Lind L and Ingelsson E. Associations of Circulating Protein Levels With Lipid Fractions in the General Population (2018) Arteriosclerosis, Thrombosis, and Vascular Biology, doi:/10.1161/ATVBAHA.118.311440
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Frändberg S, Asp J, Waldner B, Holgersson J and Palmqvist L. Concentration of the CDCP1 protein in human cord plasma may serve as a predictor of hematopoietic stem and progenitor cell content. (2018) Stem Cell Research, doi.org/10.1016/j.scr.2018.03.008
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Franzén B, Alexeyenko A, Kamali-Moghaddam M, Hatschek T, Kanter L, Ramqvist T, Kierkegaard G, Auer G, Landegren U and Lewensohn R. Protein profiling of fine needle aspirates reveals subtype‐associated immune signatures and involvement of chemokines in breast cancer. (2018) Molecular Oncology, doi.org/10.1002/1878-0261.12410
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Franzén B, Kamali‐Moghaddam M,  Alexeyenko A, Hatschek T, Becker S, Wik L, Kierkegaard J, Eriksson A, Reddy Muppani N, Auer G, Landegren U and Lewensohn R. A fine needle aspiration‐based protein signature discriminates benign from malignant breast lesions. (2018) Molecular Oncology, DOI: 10.1002/1878-0261.12350
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Gezelius E, Flou Kristensen A, Bendahl P, Hisada Y, Risom Kristensen S, Ek L, Bergman B, Wallberg M, Falkmer U, Mackman N, Pedersen S and Belting M. Coagulation biomarkers and prediction of venous thromboembolism and survival in small cell lung cancer: A sub-study of RASTEN – A randomized trial with low molecular weight heparin. (2018) PLOS ONE, doi: 10.1371/journal.pone.0207387
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Gupta V and Bernardini M. Algorithms Used in Ovarian Cancer Detection: A Minireview on Current and Future Applications (2018) Journal of Applied Laboratory Medicine, DOI: 10.1373/jalm.2017.025817
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Grufman H, Yndigegn T, Gonçalves I, Nilsson J and Schiopu A. Elevated IL-27 in patients with acute coronary syndrome is associated with adverse ventricular remodeling and increased risk of recurrent myocardial infarction and cardiovascular death (2018) Cytokine, doi.org/10.1016/j.cyto.2017.11.002
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Halak S, Östling G, Edsfeldt A, Kennbäck C, Dencker M, Gonçalves I and Asciutto G. Spotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms (2018) Cerebrovascular Diseases Extra, doi.org/10.1159/000485258
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Herder C, Kannenberg J, Carstensen-Kirberg M, Strom A, Bönhof G, Rathmann W, Huth C, Koenig W, Heier M, Krumsiek J, Peters A, Meisinger C, Roden M, Thorand B and Ziegler D. A Systemic Inflammatory Signature Reflecting Crosstalk Between Innate and Adaptive Immunity Is Associated With Incident Polyneuropathy: KORA F4/FF4 Study (2018) Diabetes, doi: 10.2337/db18-0060
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Holm Nielsen S, Tengryd C, Edsfeldt A, Brix S, Genovese F, Bengtsson E, Karsdal M, Leeming D, Nilsson J and Goncalves I. Markers of Basement Membrane Remodeling Are Associated With Higher Mortality in Patients With Known Atherosclerosis. (2018) Journal of the American Heart Association, DOI: 10.1161/JAHA.118.009193
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Johansson M, Ricci F, Aung N, Sutton R, Melander O and  Fedorowski A. Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension (2018) Hypertension, doi.org/10.1161/HYPERTENSIONAHA.117.10365
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Johansson M, Ricci F, Aung N, Sutton R, Melander O and  Fedorowski A. Inflammatory biomarker profiling in classical orthostatic hypotension: Insights from the SYSTEMA cohort (2018) Int. J. Cadiol., doi.org/10.1016/j.ijcard.2017.12.020
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Kasaian M, Lee J, Brennan A, Danto S, Black K, Fitz L and Dixon A. Proteomic analysis of serum and sputum analytes distinguishes controlled and poorly-controlled asthmatics. (2018) Journal of the British Society for Allergy and Clinical Immunology, doi.org/10.1111/cea.13151
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Kulasingam A, Hvas A-M, Lerkevang Grove E, Løkke Funck K and Dalby Kristensen S. Detection of biomarkers using a novel proximity extension assay in patients with ST-elevation myocardial infarction. (2018) Thrombosis Research, doi.org/10.1016/j.thromres.2018.10.011
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Kuschnerus K, Straessler E, Müller M, Lüscher T, Landmesser U and Kränkel N. Increased Expression of miR-483-3p Impairs the Vascular Response to Injury in Type 2 Diabetes. (2018) Diabetes, doi.org/10.2337/db18-0084
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Lagali N, Badian R, Liu X, Feldreich T, Ärnlöv J, Paaske Utheim T, Dahlin L and Rolandsson O. Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9. (2018) Scientific Reports, DOI:10.1038/s41598-018-32410-5
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Lagerstedt L, Egea-Guerrero J, Rodríguez-Rodríguez A, Bustamante A, Montaner J, El Rahal A, Andereggen R, Rinaldi L, Sarrafzadeh A, Schaller K and Sanchez J-C. Early measurement of interleukin-10 predicts the absence of CT scan lesions in mild traumatic brain injury. (2018) PLOS ONE, doi.org/10.1371/journal.pone.0193278
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Lampinen M, Vessby J, Fredricsson A, Wanders A, Rorsman F and Carlson M. High Serum sCD40 and a Distinct Colonic T Cell Profile in Ulcerative Colitis Associated With Primary Sclerosing Cholangitis. (2018) Journal of Crohn’s and Colitis, doi.org/10.1093/ecco-jcc/jjy170
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Landegren U, Al-Amin R and Björkesten J. A myopic perspective on the future of protein diagnostics. (2018) New Biotechnology, doi.org/10.1016/j.nbt.2018.01.002
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Lareyre F, Moratal C, Chikande J, Jean-Baptiste E, Hassen-Khodja R, Neels J, Chinetti G and Raffort J. Investigation of Plasma Inflammatory Profile in Diabetic Patients With Abdominal Aortic Aneurysm: A Pilot Study (2018) Vascular and Endovascular Surgery, doi:/10.1177/1538574418784717
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Lendvai N, Tsakos I, Devlin S.,Schaffer W, Hassoun H, Lesokhin A, Landau H, Korde H, Mailankody S, Smith E, Chung D, Koehne G, Shah G, Alexander A, Patel M, Ballagi A, Grundberg I, Giralt S and Landgren O. Predictive biomarkers and practical considerations in the management of carfilzomib-associated cardiotoxicity (2018) Leukemia & Lymphoma, doi.org/10.1080/10428194.2017.1403020
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Manor O, Zubair N, Conomos M, Xu X, Rohwer J, Krafft C, Lovejoy J and Magis A. A Multi-omic Association Study of Trimethylamine N-Oxide. (2018) Cell Reports, DOI: 10.1016/j.celrep.2018.06.096
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Memon A, Sundquist K,  PirouziFard M,  Elf J,  Strandberg K,  Svensson P,  Sundquist J and Zöller B. Identification of novel diagnostic biomarkers for deep venous thrombosis. (2018) British Journal of Haematology, doi.org/10.1111/bjh.15206
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Monaghan T, Mullish B, Patterson J, Wong G, Marchesi J, Xu H, Jilani T and Kao D. Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-fibroblast growth factor pathway. (2018) Gut Microbes, doi: 10.1080/19490976.2018.1506667
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Qian J, Tikk K, Werner S, Balavarca Y, Saadat M, Hechtner M and Brenner H. Biomarker discovery study of inflammatory proteins for colorectal cancer early detection demonstrated importance of screening setting validation. (2018) Journal of Clinical Epidemiology, DOI: 10.1016/j.jclinepi.2018.07.016
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Tewari S, Renney G, Brewin J, Gardner K, Kirkham F, Inusa B, Barrett J, Menzel S, Thein S-L, Ward M and Rees D. Proteomic Analysis Of Plasma From Children With Sickle Cell Anemia And Silent Cerebral Infarction (2018) Haematolgica, Doi:10.3324/haematol.2018.187815
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Timotin A, Cinato M,Boal F, Dejean S, Anesia R, Arnaut O, Lagente C, Roncalli J, Desmoulin F, Tronchere H and Kunduzova O. Differential protein profiling as a potential multi-marker approach for obese patients with heart failure: A retrospective study. (2018) Scientific Reports, doi:, 10.1038/s41598-018-26118-9
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Toribio M, Fitch K, Stone L, Zanni M, Loa J, de Filippi C, Sponseller C, Lee H, Grundberg I, Thompson M, Aberg J and Grinspoon S. Assessing statin effects on cardiovascular pathways in HIV using a novel proteomics approach: Analysis of data from INTREPID, a randomized controlled trial. (2018) EBioMedicine, doi.org/10.1016/j.ebiom.2018.08.039
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Tromp J, Westenbrink D, Ouwerkerk W, van Veldhuisen D, Samani N, Ponikowski P, Metra M, Anker S, Cleland J, Dickstein K,  Filippatos G, van der Harst P, Lang, C, Ng L, Zannad F, Zwinderman A, Hillege H, van der Meer P and Voors A. Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction. (2018) JACC, doi.org/10.1016/j.jacc.2018.06.050
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Vossen A, van der Zee1 H, Davelaar N, Mus A, van Doorn M and Prens E. Apremilast for moderate hidradenitis suppurativa: no significant change in lesional skin inflammatory biomarkers. (2018) Journal of the European Academy of Dermatology and Venereology, doi.org/10.1111/jdv.15354
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Wigren M, Svenugnsson E, Yao Mattisson I, Gustafsson J, Gunnarsson I, Zickert A, Elvin K, Jensen-Urstad K, Bengtsson A, Gullstrand B, Nordin Fredrikson G and Nilsson J. Cardiovascular disease in systemic lupus erythematosus is associated with increased levels of biomarkers reflecting receptor-activated apoptosis (2018) Atherosclerosis, doi: 10.1016/j.atherosclerosis.2018.01.022
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Yeung V, Webber J, Dunlop E, Morgan H, Hutton J, Gurney M, Jones E, Falcon-Perez J, Tabi Z, Errington R and Clayton A. Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma (2018) Nanoscale, doi/10.1039/C8NR02417K
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Ahsan M, Ek W, Rask-Andersen M, Karlsson T, Lind-Thomsen A, Enroth S, Gyllensten U and Johansson Å. The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases. (2017) PLOS Genetics, DOI: 10.1371/journal.pgen.1007005
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Andersson E, Bergemalm D, Kruse R, Neumann G, D’Amato M, Repsilber D, and Halfvarson J. Subphenotypes of inflammatory bowel disease are characterized by specific serum protein profiles. (2017) PLOS One, doi.org/10.1371/journal.pone.0186142
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Bergthorsdottir R, Ragnarsson O, Skrtic S, Glad K, Nilsson S, Louis Ross I, Leonsson-Zachrisson M and Johannsson G. Visceral Fat and Novel Biomarkers of Cardiovascular Disease in Patients with Addison’s Disease; a case-control study (2017) The Journal of Clinical Endocrinology & Metabolism, doi.org/10.1210/jc.2017-01324
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Bryan R, Gordon N, Abbotts B, Zeegers M, Cheng K, James N and  Ward D. Multiplex screening of 422 candidate serum biomarkers in bladder cancer patients identifies syndecan-1 and macrophage colony stimulating factor 1 as prognostic indicators. (2017) Translational Cancer Research, doi:10.21037/tcr.2017.04.19
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Bäckryd E, Lind A-L, Thulin M,  Larsson A, Gerdle B and Gordh T. High levels of cerebrospinal fluid chemokines point to the presence of neuroinflammation in peripheral neuropathic pain: a cross-sectional study of 2 cohorts of patients compared with healthy controls. (2017) Pain, doi:10.1097/j.pain.0000000000001061
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Bäckryd E, Tanum L, Lind A-L, Larsson A and Gordh T. Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. (2017) Journal of Pain Research, https://doi.org/10.2147/JPR.S128508
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Carlsson A,Ingelsson E, Sundström J, Carrero J, Gustafsson S, Feldreich T, Stenemo M, Larsson A, Lind L and Ämlöv J. Use of Proteomics To Investigate Kidney Function Decline over 5 Years. Clinical Journal of the American Society of Nephrology (2017), doi: 10.2215/CJN.08780816
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Cornelis M,   Gustafsson S,  Ärnlöv J, Elmståhl S, Söderberg S,  Sundström J,   Michaëlsson K,  Lind L and Ingelsson E. Targeted proteomic analysis of habitual coffee consumption. (2017) Journal of Internal Medicine, doi.org/10.1111/joim.12703
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Flintholm Raft K, Frestad D, Michelsen M, Suhrs H, Rask A, Nilsson M, Hermann T and Prescott E. Peripheral Endothelial Function and Coronary Flow Velocity Reserve Are Not Associated in Women with Angina and No Obstructive Coronary Artery Disease: The iPOWER Study (2017) Journal of Vascular Research, doi.org/10.1159/000479374
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Gerdle B, Ghafouri B, Ghafouri N, Bäckryd E and Gordh T. Signs of ongoing inflammation in female patients with chronic widespread pain. A multivariate, explorative, cross-sectional study of blood samples. (2017) Medicine, http://dx.doi.org/10.1097/MD.0000000000006130
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Gohar A, Gonçalves I, Vrijenhoek J, Haitjema S, van Koeverden I, Nilsson J, de Borst G, de Vries J-P, Pasterkamp G, den Ruijter H, Björkbacka H and de Jager S. Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis (2017) International Journal of Cardiology, http://dx.doi.org/10.1016/j.ijcard.2017.03.101
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Hage C, Michaëlsson E, Linde C, Donal E, Daubert J-C, Gan L-M and Lund L. Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction. (2017) Circulation: Cardiovascular Genetics, doi.org/10.1161/CIRCGENETICS.116.001633
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Harlid S, Myte R and Van Guelpen B. The Metabolic Syndrome, Inflammation, and Colorectal Cancer Risk: An Evaluation of Large Panels of Plasma Protein Markers Using Repeated, Prediagnostic Samples. (2017) Mediators of Inflammation, doi:10.1155/2017/4803156
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Hill L, Di Pietro V, Hazeldine J, Davies D, Tomman E, Logan A and Belli A. Cystatin D (CST5): An ultraearly inflammatory biomarker of traumatic brain injury. (2017)  Scientific Reports, DOI:10.1038/s41598-017-04722-5
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Hofmann R, Tornvall P, Witt N, Alfredsson J, Svensson L, Jonasson L and Nilsson L. Supplemental oxygen therapy does not affect the systemic inflammatory response to acute myocardial infarction (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12716
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Jónsdóttir B, Jaworowski Å, San Miguel C and Melander O. IL-8 predicts early mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation (2017) BMC Pulmonary Medicine, DOI: 10.1186/s12890-017-0377-7
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Kim J, Tomalin L, Lee J, Fitz L, Berstein G, Correa-da Rosa J, Garcet S, Lowes M, Valdez H, Wolk R, Suarez-Farinas M and Krueger J. Reduction of inflammatory and cardiovascular proteins in the blood of psoriasis patients; differential responses between tofacitinib and etanercept after 4 weeks of treatment. (2017) Journal of Investigative Dermatology, doi:10.1016/j.jid.2017.08.040A
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Kupcova Skalnikova H, Cizkova J, Cervenka J and Vodicka P. Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research (2017) Int. J. Mol. Sci., doi:10.3390/ijms18122697
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Lakshmikanth T, Olin A, Chen Y, Mikes J, Fredlund E, Remberger M, Omazic B and Brodin P. Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation (2017) Cell Reports, doi.org/10.1016/j.celrep.2017.08.021
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Langley S, Willeit K, Didangelos A, Perisic Matic L, Skroblin P, Barallobre-Barreiro J, Lengquist MN, Rungger G,Kapustin A, Kedenko L, Molenaar C, Lu R, Barwari T, Suna G, Yin X, Iglseder B,Paulweber B, Willeit P, Shalhoub J, Pasterkamp G,Davies A, Monaco C, Hedin U, Shanahan C, Willeit J, Kiechl S and Mayr M. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques. (2017) Journal of  Clinical Investigation, doi:10.1172/JCI86924
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Larssen P, Wik L, Czarnewski P, Eldh M, Lof L, Ronquist J, Dubois L, Freyhult E, Gallant C, Oelrich J, Larsson A, Ronquist G, Villablanca E, Landegren U, Gabrielsson S and Kamali-Moghaddam M. Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay (2017) Molecular & Cellular Proteomics, doi: 10.1074/mcp.M116.064725
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Mahdessian H, Perisic Matic L, Lengquist M, Gertow K, Sennblad B, Baldassarre D, Veglia F, Humphries S, Rauramaa R, de Faire U, Smit A, Giral P, Kurl S, Mannarino E, Tremoli E, Hamsten A, Eriksson P, Hedin U, Mälarstig A, IMPROVE study group. Integrative Studies Implicate Matrix Metalloproteinase 12 as a Culprit Gene for Large-Artery Atherosclerotic Stroke. (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12655
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Mazurkiewicz M, Hillert E-K, Wang X, Pellegrini P, Hägg Olofsson M, Selvaraju K, D’Arcy P and Linder S. Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition. (2017) Oncotarget, doi: 10.18632/oncotarget.15501
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Mohammad M, Noc N, Lang I, Holzer M, Clemmensen P, Jensen U, Metzler B and Erlinge, D. Proteomics in Hypothermia as Adjunctive Therapy in Patients with ST-Segment Elevation Myocardial Infarction: A CHILL-MI Substudy (2017) Therapeutic Hypothermia and Temperature Management, doi.org/10.1089/ther.2016.0041
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Molin C, Westerberg E and Rostedt Punga A. Profile of upregulated inflammatory proteins in sera of Myasthenia Gravis patients (2017) Scientific Reports, doi:10.1038/srep39716.
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Mrazek F, Schneiderova P, Kriegova E, Raida L, Kuba A, Gajdos P, KönigovaJana N, Onderkova J and Ambruzova Z. Profile of Inflammation-Associated Proteins in Early Post-Transplant Samples of Patients After Allogeneic Hematopoietic Stem Cell Transplantation: a Preliminary Study. (2017) Archivum Immunologiae et Therapiae Experimentalis, DOI: 10.1007/s00005-016-0446-2.
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Panezai J, Ghaffar A, Altamash M, Sundqvist K-G, Engström P-E and Larsson A. Correlation of serum cytokines, chemokines, growth factors and enzymes with periodontal disease parameters. (2017) PLOS ONE, doi.org/10.1371/journal.pone.0188945
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Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum J, Alexander V, Willeit J, Kiech S and Mayr M. Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III (2017) Journal of the American College of Cardiology, Vol 69 (7) DOI: 10.1016/j.jacc.2016.11.065 (Online Appendix)
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Petrackova A, Smrzova A, Gajdos P, Schubertova M, Schneiderova P, Kromer P, Snasel V, Skacelova M, Mrazek F, Zadrazil J, Horak P and Kriegova E. Serum protein pattern associated with organ damage and lupus nephritis in systemic lupus erythematosus revealed by PEA immunoassay. (2017) Clinical Proteomics, DOI: 10.1186/s12014-017-9167-8
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Price N, Magis A, Earls J, Glusman G, Levy R, Lausted C, McDonald D, Kusebauch U, Moss C, Zhou Y, Qin S, Moritz R, Brogaard K, Omenn G, Lovejoy J and Hood L. A wellness study of 108 individuals using personal, dense, dynamic data clouds. (2017) Nature Biotechnology, doi:10.1038/nbt.3870
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Roerink M, Knoop H, Bronkhorst E, Mouthaan H, Luuk Hawinkels J, Joosten L and van der Meer J. Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment. (2017) Journal of Translational Medicine, doi: 10.1186/s12967-017-1371-9
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Savola P, Brück O, Olson T, Kelkka T, Kauppi M, Kovanen P, Kytölä S, Sokka-Isler T, Loughran T, Leirisalo-Repo M and Mustjoki S. Somatic STAT3 mutations in the Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia. (2017) Haematologica, doi:10.3324/haematol.2017.175729
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Schiza A, Wenthe J, Mangsbo S, Eriksson E, Nilsson A, Tötterman T, Loskog A and Ulenhag G. Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients. (2017) Journal of Translational Medicine, DOI: 10.1186/s12967-017-1182-z
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Schwenk J, Omenn G, Sun Z, Campbell D, Baker M, Overall C, Aebersold R, Moritz R and Deutsch E. The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays (2017) Journal of Proteome Research, doi:10.1021/acs.jproteome.7b00467
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Shen Q, Björkesten J, Galli J, Ekman D, Broberg J, Nordberg N, Tillander A, Kamali-Moghaddam M, Tybring G and Landegren U. Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays. (2017) Clinical Chemistry and Laboratory Medicine, doi: 10.1515/cclm-2017-0648
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Skau E, Henriksen E, Wagner P, Hedberg P, Siegbahn A and Leppert J. GDF-15 and TRAIL-R2 are powerful predictors of long-term mortality in patients with acute myocardial infarction (2017) European Journal of Preventive Cardiology, doi.org/10.1177/2047487317725017
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Smith G and Gerszten R. Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease (2017) Circulation, doi.org/10.1161/CIRCULATIONAHA.116.025446
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Solheim N, Östlund, S, Gordh T and Rosseland L.A. Women report higher pain intensity at a lower level of inflammation after knee surgery compared with men. (2017) Pain Reports, doi: 10.1097/PR9.0000000000000595
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Stenemo M, Nowak C, Byberg L, Sundström J, Giedraitis V, Lind L, Ingelsson E, Fall T and Ärnlöv J. Circulating proteins as predictors of incident heart failure in the elderly (2017) European Journal of Heart Failure, doi: 10.1002/ejhf.980
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Stensson N, Ghafouri B, Gerdle B and Ghafouri N. Alterations of anti-inflammatory lipids in plasma from women with chronic widespread pain – a case control study (2017) Lipids in Health &  Disease, DOI: 10.1186/s12944-017-0505-7
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Sukma Dewi I, Gidlöf O, Hollander Z, Lam K, Benson M, Braun O, Nilsson J, Tebbutt S, Ng R,  Öhman J, McManus B and Smith G. Immunological Serum Protein Profiles for Noninvasive Detection of Acute Cellular Rejection After Heart Transplantation. (2017) Journal of the American College of Cardiology, doi.org/10.1016/j.jacc.2017.10.012
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Uderhardt S, Ackermann J, Fillep T, Hammond V, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner K, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz‑Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins P, Schabbauer G, Mackman N, Voehringer D, Nadler J, Lee J, Massberg S, Rauh M, Kiechl S, Schett G, O’Donnell V and Krönke G. Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. JEM (2017), doi.org/10.1084/jem.20161070
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Vallejo J,Dunér P, Fredrikson G, Nilsson J and Bengtsson E. Autoantibodies against aldehyde-modified collagen type IV are associated with risk of development of myocardial infarction. (2017) Journal of Internal Medicine, doi/10.1111/joim.12659/full
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Villani A-C, Satija1 R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager P, Rozenblatt-Rosen O, Lane A, Haniffa M, Regev A and Hacohen N. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. (2017) Science, DOI: 10.1126/science.aah4573
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West N, Corrigan J, Owen R, Hoole S, Brown A, Blatcher S and Newby, A. Percutaneous Sampling of Local Biomolecule Gradients Across Coronary Artery Atherosclerotic Plaques.(2017) JACC: Basic to Translational Science, doi: 10.1016/j.jacbts.2017.07.007
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Willeit K, Pechlaner R, Willeit P, Skroblin P, Paulweber B, Schernthaner C, Toell T, Egger G, Weger S, Oberhollenzer M, Kedenko L, Iglseder B, Bonora E, Schett G, Mayr M, Willeit J and Kiechl S. Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation. JAMA Cardiology (2017), doi:10.1001/jamacardio.2017.0064
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Yao Mattisson I, Björkbacka H, Wigren H, Edsfeldt A, Melander O, Nordin Fredrikson G, Bengtsson E, Gonçalves I, Orho-Melander M, Engström G, Almgren P and Nilsson J. Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease. (2017) EBioMedicine, doi.org/10.1016/j.ebiom.2017.11.023
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Yeh C, Adusumilli R, Kullolli M, Mallick P, John E and Pitteri S. Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer. (2017) Biomarker Research, DOI 10.1186/s40364-017-0110-y
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Zhang W, Ambikan A, Sperk M, van Domselaar R, Nowak P, Noyan K, Russom A,, Sönnerborg A and Neogi U. Transcriptomics and Targeted Proteomics Analysis to Gain  Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers. (2017) EBioMedicine, doi:10.1016/j.ebiom.2017.11.031
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Zwicker S, Lira-Junior R, Höög C, Almer S and Boström E. Systemic Chemokine Levels with “Gut-Specific” Vedolizumab in Patients with Inflammatory Bowel Disease—A Pilot Study (2017) International Journal of Molecular Sciences, doi: 10.3390/ijms18081827
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2016

Andreasson U, Blennow K and Zetterberg H. Update on ultrasensitive technologies to facilitate research on blood biomarkers for central nervous system disorders. Alzheimer’s & Dementia (2016), 3, 98-102.
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Berggrund M, Ekman D, Gustavsson I, Sundfeldt K, Olovsson M, Enroth S and Gyllensten U. Protein Detection Using the Multiplexed Proximity Extension Assay (PEA) from Plasma and Vaginal Fluid Applied to the Indicating FTA Elute Micro Card. J. Circ. Biomark. (2016), 5:9. doi:10.5772/64000
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Berntson L, Hedlund-Treutiger I and Alving K. Anti-inflammatory effect of exclusive enteral nutrition in patients with juvenile idiopathic arthritis. (2016) Clinical and Experimental Rheumatology, 34(5):941-945
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Carlsson A, Sundström J, Carrero J, Gustafsson S, Stenemo M, Larsson A, Lind L and Ärnlöv J. Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria. (2016) Eur J. Prev. Cardiol., DOI: 10.1177/2047487316676134.
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Chen H, Knebel P and Brenner H. Empirical evaluation demonstrated importance of validating biomarkers for early detection of cancer in screening settings to limit the number of false-positive findings. (2016) Journal Clinical Epidemiology, doi.org/10.1016/j.jclinepi.2016.01.022
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Darmanis S, Gallant C, Marinescu V,  Niklasson M, Segerman A,  Flamourakis G,  Fredriksson S, Assarsson E, Lundberg M, Nelander S, Westermark B and  Landegren U. Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells. (2016) Cell Reports 14, 380-389.
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Edsfeldt A, Bengtsson E, Asciutto G, Dunér P, Björkbacka H, Fredrikson G.N, Nilsson J, Goncalves I. High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy. Cerebrovasc Dis. (2016); 41:199-203
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Edfeldt K, Daskalakis K, Bäcklin C, Norlén O, Tiensuu Janson E, Westin G, Hellman P and Stålberg P. DcR3, TFF3 and Midkine are Novel Serum Biomarkers in Small Intestinal Neuroendocrine Tumors. (2016) Neuroendocrinology, DOI: 10.1159/000452891
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Eisenberg T. et. al. Cardioprotection and lifespan extension by the natural polyamine spermidine (2016) Nature Medicine, DOI: 10.1038/nm.4222.
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Enroth S, Hallmans G, Grankvist K and Gyllensten, U. (2016) Effects of long-term storage time and original sampling month on biobank plasma protein concentrations. EBioMedicine, 201608.038
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Genshaft A, Li S, Gallant C, Darmanis S, Prakadan S, Ziegler C, Lundberg M, Fredriksson S, Hong J, Regev A, Livak K, Landegren U and Shalek A. (2016) Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. Genome Biology, 17:188 DOI 10.1186/s13059-016-1045-6
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Goncalves I, Edsfeldt A, Colhoun H, Shore A, Palombo C, Natali A, Nordin Fredrikson G, Björbacka H, Wigren M, Bengtsson E, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Gates P, Khan F, Looker H, Adams F, Belch J, Pinnola S, Venturi E, Kozakova M, Gan L, Schnecke C and Nilsson J. (2016) Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovascular Disorders, 16:171 DOI 10.1186/s12872-016-0346-8
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Gonçalves I, Hultman K, Dunér, P, Edsfeldt A, Hedblad B, Nordin Fredrikson G, Björkbacka H, Nilsson J and Bengtsson E. (2016) High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.  Open Heart.  3: doi:10.1136
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Grönberg C, Asciutto G, Persson A, Nordin Fredrikson G, Nilsson J, Gonçalves I and Björkbacka H. (2016) Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up. Cytokine, doi.org/10.1016/j.cyto.2016.06.009
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Huang B, Svensson P, Ärnlov J, Sundström J, Lind L and Ingelsson E. (2016) Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies. Atherosclerosis, 10.1016/j.atherosclerosis.2016.09.014
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Jahn L , Lee Hartline, Nagashree Rao, Brent Logan, Justin J Kim, Kevin Aylor , Li-Ming Gan, Helena U Westergren, and Eugene J Barrett. (2016) Insulin enhances endothelial function throughout the arterial tree in healthy but not metabolic syndrome subjects. J. Clin. Endocrinol. Metab.  doi: 10.1210/jc.2015-3293
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Kaihola H, Yaldir F, Hreinsson J, Hörnaeus K, Bergquist J, Olivier J, Åkerud H and Sundström-Poromaa I. (2016) Effects of Fluoxetine on Human Embryo Development. Frontiers in Cellular Neuroscience, doi: /10.3389/fncel.2016.00160
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Lind L, Sundström J, Stenmo M, Hagström E and Ärnlöv J. (2016) Discovery of new biomarkers for atrial fibrillation using a custom-made proteomics chip. Heart, 10.1136/heartjnl-2016-309764
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Loskog A, Maleka A, Mangsbo S, Svensson E, Lundberg C, Nilsson A, Krause J, Agnarsdottir M, Sundin A, Ahlström H, Tötterman T and Ullenhag G. (2016) Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients. British Journal of Cancer  114, 872–880. doi:10.1038/bjc.2016.42
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Lund N, Gränsbo, K, Wernersson C and Melander O. (2016) Cardiometabolic biomarkers are predictors of readmission and death in patients hospitalized for acute dyspnea  Am. J. Emergency Med., http://dx.doi.org/10.1016/j.ajem.2016.12.048
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Mailankody S, Devlin S, Korde N, Lendvai N, Lesokhin A, Landau H, Hassoun H, Ballagi A, Ekman D, Chung D, Patel M, Koehne G, Giralt S and Landgren O. (2016) Protein profiling in plasma cell disorders: a feasibility study. Leukemia & Lymphoma, DOI: 10.1080/10428194.2016.1258699
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Moen A, Lind A-L, Thulin M, Kamali-Moghaddam M, Røe C, Gjerstad J and Gordh T. (2016) Inflammatory serum protein profiling of patients with lumbar radicular pain one year after disc herniation. Int. J. Inflammation  Article ID 3874964.
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Schiopu A, Bengtsson E, Goncalves I, Nilsson J, Nordin Fredrikson G and Björbacka H. Associations Between Macrophage Colony-Stimulating Factor and Monocyte Chemotactic Protein 1 in Plasma and First-Time Coronary Events: A Nested Case–Control Study. (2016) J. Am Heart Assoc., 10.1161/JAHA.115.002851
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Schneiderova P, Pika T, Gajdos P, Fillerova R, Kromer P, Kudelka M, Minarik J, Papajik T, Scudla V and Kriegova E. Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma. (2016) Oncotarget.
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Shaw P, Yang Y, Gonzalez J, Kuruvilla S, Gottbrecht M, Epstein F,Gan L, Keeley E, Kramer C, Salerno M. Extracellular volume by CMR is associated with serum biomarkers of extracellular matrix turnover and inflammation in hypertensive heart disease. Journal of Cardiovascular Magnetic Resonance (2016)  doi:10.1186/1532-429X-18-S1-O103
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Söderlund S, Christiansson L, Persson I, Hjorth-Hansen H, Richter J, Simonsson B, Mustjoki S, Olsson-Strömberg U and Loskog A. Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli. (2016) Leukemia Research, DOI: 10.1016/j.leukres.2016.09.019
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Westergren H, Svedlund S, Momo R, Blomster J, Wåhlander K, Rehnström E, Greasley P, Regina Fritsche‑Danielson R, Oscarsson J and Gan L-M. Insulin resistance, endothelial function, angiogenic factors and clinical outcome in non‑diabetic patients with chest pain without myocardial perfusion defects. Cardiovasc Diabetol (2016) 15:36 DOI 10.1186
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Yang X, Tang Y, Alt, R, Xie, X and Lia, F. Emerging techniques for ultrasensitive protein analysis. Analyst (2016), 10.1039/C6AN00059B. (Review article).
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2015

Asciutto G, Dias NV, Edsfeldt A, Nitulescu M, Persson A, Nilsson M, Dunér P, Nilsson J, Gonçalves I. Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke. PLoS One. (2015) Mar 24;10(3):e0121086. doi: 10.1371/journal.pone.0121086.
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Chen H, Zucknick M, Werner S, Knebel P, Brenner H. Head-to-Head Comparison and Evaluation of 92 Plasma Protein Biomarkers for Early Detection of Colorectal Cancer in a True Screening Setting. Clin Cancer Res. (2015) Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051. Epub 2015 May 26.
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Christiansson L, Söderlund S, Mangsbo S, Hjort-Hansen H, Höglund M, Markevärn B, Richter J, Stenke L, Mustjoki S, Loskog A, Olsson-Strömberg U. The tyrosine kinase inhibitors imatinib and dasatinib reduce myeloid suppressor cells and release effector lymphocyte responses. Mol Cancer Ther. (2015) May;14(5):1181-91. doi: 10.1158/1535-7163.MCT-14-0849.
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Enroth S, Bosdotter Enroth S, Johansson Å, Gyllensten U. Effect of genetic and environmental factors on protein biomarkers for common noncommunicable disease and use of personally normalized plasma protein profiles (PNPPP). Biomarkers. (2015) Sep;20(6-7):355-64. doi: 10.3109/1354750X.2015.1093546.
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Enroth S, Enroth SB, Johansson Å, Gyllensten U. Protein profiling reveals consequences of lifestyle choices on predicted biological aging. Sci Rep. (2015) Dec 1;5:17282. doi: 10.1038/srep17282
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Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Strain D, Kahn F, Looker HC, Adams F, Belch J, Pinnoli S, Venturi E, Kozakova M, Gan LM, Schnecke V, Nilsson J. Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes. Arterioscler Thromb Vasc Biol. (2015) May 7. pii: ATVBAHA.115.305631.
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Greenwood C, Ruf D, Kirvell S, Johnson G, Dhillon HS, Bustin SA. Proximity assays for sensitive quantification of proteins. Biomol Det and Quantif. (2015). 4:10-16.
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Helseth R, Weiss T, Opstad T, Siegbahn A, Solheim S, Freynhofer M, Huber K, Arnesen H and Seljeflot S. Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction. Thrombosis Res. (2015), 136: 1240-1244
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Isgren A, Jakobsson J, Pålsson E, Ekman C J, Johansson A G.M., Sellgren C, Blennow K, Zetterberg H and Landén M. Increased cerebrospinal fluid interleukin-8 in bipolar disorder patients associated with lithium and antipsychotic treatment. Brain Behav Immun. (2015) Jan;43:198-204. doi: 10.1016/j.bbi.2014.10.001. Epub 2014 Oct 14.
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Kalla R, Kennedy NA, Hjelm F, Modig E, Sundell M, Söderholm J, Andreassen B, Bergemalm D, Ventham NT, Hjortswang H, Petr R, Vatn MH, Halfvarson J, Gullberg M, Satsangi J. OC-015 Proximity extension assay technology identifies novel serum biomarkers for predicting inflammatory bowel disease: IBD character consortium. Gut (2015);64:A8 doi:10.1136/gutjnl-2015-309861.15
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Kaudewitz D, Skroblin P, Bender LH, Barwari T, Willeit P, Pechlaner R, Sunderland NP, Willeit K, Morton A, Armstrong PC, Chan MV, Lu R, Yin X, Gracio F, Dudek K, Langley S, Zampetaki A, de Rinaldis E, Ye S, Warner TD, Saxena A, Kiechl S, Storey R, Mayr M. Association of MicroRNAs and YRNAs with Platelet Function. Circ Res. (2015) Feb 5;118(3):420-32. doi: 10.1161/CIRCRESAHA
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Larsson A, Carlsson L, Gordh T, Lind A-L, Thulin M, Kamali-Moghaddam M. The effects of age and gender on plasma levels of 63 cytokines. Clin Cancer Res. (2015) Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051.
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Larsson A, Carlsson L, Lind A-L, Gordh T, Bodolea C, Kamali-Moghaddam M, Thulin M. The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid. Cytokine. (2015) Jul 15. pii: S1043-4666(15)30020-X. doi: 10.1016/j.cyto.2015.07.010.
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Lind L, Ärnlöv J, Lindahl B, Siegbahn A, Sundström J, Ingelsson E. Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis. Atherosclerosis. 2015 Jul 14;242(1):205-210. doi: 10.1016/j.atherosclerosis. (2015).07.023.
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Lind L, Siegbahn A, Lindahl B, Stenemo M, Sundström J, Ärnlöv J. Discovery of new risk markers for ischemic stroke using a novel targeted proteomics chip. Stroke. (2015) Dec;46(12):3340-7. doi: 10.1161/STROKE AHA.115.010829
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Mahboob S, Ahn SB, Cheruku HR, Cantor D, Rennel E, Fredriksson S, Edfeldt G, Breen EJ, Khan A, Mohamedali A, Muktadir MG, Ranganathan S, Tan S-H, Nice E, Baker MS. A novel multiplexed immunoassay identifies CEA, IL-8 and prolactin as prospectivemarkers for Dukes’ stages A-D colorectal cancers. Clinical Proteomics (2015) Apr 8;12(1):10. doi:10.1186/s12014-015-9081-x. eCollection 2015.
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Miclescu AA, Svahn M, Gordh TE. Evaluation of the protein biomarkers and the analgesic response to systemic methylene blue in patients with refractory neuropathic pain: a double-blind, controlled study. J Pain Res. (2015) Jul 15;8:387-97. doi: 10.2147/JPR.S84685. eCollection 2015.
PubMed link >

Nowak C, Sundström J, Gustafsson S, Giedraitis V, Lind L, Ingelsson E, Fall T.Protein biomarkers for insulin resistance and type 2 diabetes risk in two large community cohorts. Diabetes. (2015) Sep 29. pii: db150881.
PubMed link >

Wigren M, Rattik S, Hultman K, Björkbacka H, Nordin-Fredrikson G, Bengtsson E, Hedblad B, Siegbahn A, Goncalves I, Nilsson J. Decreased levels of stem cell factor in subjects with incident coronary events. J Intern Med. (2015) Oct 14. doi: 10.1111/joim.12443.
PubMed link >

Wiklund K, Gränsbo K, Lund N, Peyman M, Tegner L, Toni-Bengtsson M, Wiel M, Melander O. Inflammatory biomarkers predicting prognosis in patients with acute dyspnea. Am. J. Emerg. Med. (2015) doi: 10.1016/j.ajem.2015.10.052.
PubMed link >


2014

Assarsson E, Lundberg M, Holmquist G, Björkesten J, Thorsen SB, Ekman D, Eriksson A, Rennel Dickens E, Ohlsson S, Edfeldt G, Andersson A-C, Lindstedt P, Stenvang J, Gullberg M, and Fredriksson S. Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability. PLOS one. April 24, (2014).
Article link >

Enroth S, Johansson Å, Bosdotter Enroth S and Ulf Gyllensten U. Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. Nature Commun. (2014) Aug 22;5:4684. doi: 10.1038/ncomms5684.
PubMed link >

Hillered L, Dahlin AP, Clausen F, Chu J, Bergquist J, Hjort K, Per Enblad P and Lewén A. Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting – a technical approach. Front Neurol. (2014); 5: 245.
PubMed link >

Rattik S, Wigren M, Björkbacka H, Nordin Fredriksson G, Hedblad B, Siegbahn A, Bengtsson E, Schiopu A, Edsfeldt A, Dunér P, Grufman H, Concalves I and Nilsson J. High Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events. Arterioscler Thromb Vasc Biol. (2015) Jan;35(1):222-8. doi: 10.1161/ATVBAHA.114.304369,  Epub 2014 Oct 30.
PubMed link >

Solier C, Langen H. Antibody-based proteomics and biomarker research – current status and limitations. Proteomics. (2014) Mar;14(6):774-83. doi: 10.1002/pmic.201300334.
PubMed link >

Publications for studies in non-human species

2021

Buitrago-Molina L, Pietrek J, Noyan F, et al. Treg-specific IL-2 therapy can reestablish intrahepatic immune regulation in autoimmune hepatitis. (2021) Journal of Autoimmunity, DOI: 10.1016/j.jaut.2020.102591
Article link>

2020

Bue M, Leth Bergholt N, Kruse Jensen L, et. al. Inflammatory proteins in infected bone tissue – An explorative porcine study. (2020) Bone Reports, DOI: 10.1016/j.bonr.2020.100292
Article link>

Dommel S, Berger C, Kunath A, et. al. The Fabp4-Cre-Model is Insufficient to Study Hoxc9 Function in Adipose Tissue. (2020) Biomedicines, DOI: 10.3390/biomedicines8070184
Article link>

Kiouptsi K, Pontarollo G, Todorov H, et. al. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice. (2020) Gut Microbes, DOI: 10.1080/19490976.2020.1767463
Article link>

2019

Li Z, Rasmussen T, Rasmussen M, Li J, Henríquez Olguín C, Kot W, Nielsen D and Jensen T. The Gut Microbiome on a Periodized Low-Protein Diet Is Associated With Improved Metabolic Health.  (2019) Frontiers in microbiology, DOI: 10.3389/fmicb.2019.00709
Article link>

Taylor M, Hughes A, Walton J, Coenen-Stass A, Magiera L, Mooney L, Bell S, Staniszewska A, Sandin L, Barry S, Watkins A, Carnealli L and Hardaker E. Longitudinal immune characterization of syngeneic tumor models to enable model selection for immune oncology drug discovery. (2019) Journal for Immunotherapy of Cancer, DOI: 10.1186/s40425-019-0794-7
Article link>

2018

Löfgren M, Svala E, Lindahl A, Skiöldebrand E and Ekman S. Time-dependent changes in gene expression induced in vitro by interleukin-1β in equine articular cartilage. (2018) Research in Veterinary Science, doi.org/10.1016/j.rvsc.2018.04.013
Article link>

2015

Pauk M, Grgurevic L, Brkljacic J, Kufner V Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt J, Lin H, Volarevic S and Vukicevic S. Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice (2015) International Orthopaedics, doi: 10.1007/s00264-014-2550-4
PubMed link>

2947

Biomarker assays

~475 million

Protein data points generated

662

Publications listed on website

35

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