Olink publications - over 900 and growing rapidly

Here you will find the latest list of publications that have used Olink’s panels for protein biomarker discovery in the reported studies, or which have reviewed our technology. The publications are grouped according to year of publication, and sorted alphabetically by first author. Links are provided to the journal abstract page or  PubMed entry for each publication, or where applicable, a link to the open-access full text version of the paper. The main list details articles based on human studies, for those based on studies in non-human species, go directly to non-human study publications

Tip: To search for keywords of interest within the publication titles below, type Ctrl+F and enter your search term.

Chronological list of publications

2022

Achenbach P, Hippich M, Zapardiel-Gonzalo J, et al. A classification and regression tree analysis identifies subgroups of childhood type 1 diabetes. (2022) eBioMedicine, DOI: 10.1016/j.ebiom.2022.104118
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Alavi A, Hamzavi I, Brown K, et al. Janus kinase 1 inhibitor INCB054707 for patients with moderate-to-severe hidradenitis suppurativa: results from two phase 2 studies. (2022) British Journal of Dermatology, DOI: 10.1111/bjd.20969
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Al-Nesf MAY, Abdesselem HB, Bensmail I, et al. Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications. (2022) Nature Communications, DOI: 10.1038/s41467-022-28639-4
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Ambikan A, Yang H, Krishnan S, et al. Multiomics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity. (2022) Cell Systems, DOI: 10.1016/j.cels.2022.06.006
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Arias de la Rosa I, López-Montilla MD, Román-Rodríguez C, et al. The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast. (2022) Journal of Internal Medicine, DOI: 10.1111/joim.13447.
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Arvidsson M, Ahmed A, Säleby J, et al. Plasma matrix metalloproteinase 2 is associated with severity and mortality in pulmonary arterial hypertension. (2022) Pulmonary Circulation, DOI: 10.1002/pul2.12041
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Bapat SP, Whitty C, Mowery CT, et al. Obesity alters pathology and treatment response in inflammatory disease. (2022) Nature, DOI: 10.1038/s41586-022-04536-0
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Bao X, Xu B, Yin S, et al. Proteomic Profiles of Body Mass Index and Waist-to-Hip Ratio and their Role in Incidence of Diabetes. (2022) Journal of Clinical Endocrinology and Metabolism, DOI: 10.1210/clinem/dgac140
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Bhardwaj M, Schrotz-King P & Brenner H.  Correlation of Repeat Measurements of 27 Candidate Protein Markers for Colorectal Cancer Screening Taken Three Years and Multiple Freeze–Thaw Cycles Apart. (2022) Life, DOI: 10.3390/life12030359
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Bicvic A, Scherrer N, Schweizer J, et al. A novel biomarker panel index improves risk stratification after ischemic stroke. (2022) European Stroke Journal, DOI: 10.1177/23969873221090798
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Bjødstrup Palstrøm N, Matthhiesen R, Melholt Rasmussen L, and Beck HC. Recent Developments in Clinical Plasma Proteomics—Applied to Cardiovascular Research. (2022) Biomedicines, DOI: 10.3390/biomedicines10010162
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Bottigliengo D, Foco L, Seibler P, et al. A Mendelian randomization study investigating the causal role of inflammation on Parkinson’s disease. (2022) Brain, DOI: 10.1093/brain/awac193
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Bracco Gartner TCL, Crnko S, Leiteris L, et al. Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis. (2022) Frontiers in Cardiovascular Medicine, DOI: 10.3389/fcvm.2022.854314
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Brown JL, Townsend E, Short RD, et al. Assessing the inflammatory response to in vitro polymicrobial wound biofilms in a skin epidermis model. (2022) NPJ Biofilms and Microbiomes, DOI: 10.1038/s41522-022-00286-z
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Bowman WS, Newton CA, Linderholm AL, et al. Proteomic biomarkers of progressive fibrosing interstitial lung disease: a multicentre cohort analysis. (2022) Lancet Respiratory Medicine, DOI: 10.1016/S2213-2600(21)00503-8
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Byeon SK, Madugundu AK, Garapati K, et al. Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study. (2022) The Lancet Digital Health, DOI: 10.1016/S2589-7500(22)00112-1
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Casselbrant A, Fedorowski A, Frantz S, et al. Common physiologic and proteomic biomarkers in pulmonary and coronary artery disease. (2022) Plos One, DOI: 10.1371/journal.pone.0264376
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Ceelen D, Voors AA, Tromp J, et al. Pathophysiological pathways related to high plasma GDF-15 concentrations in patients with heart failure. (2022) European Journal of Heart Failure, DOI: 10.1002/ejhf.2424
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Chandramouli C, Ting TW, Tromp J, et al.  Sex differences in proteomic correlates of coronary microvascular dysfunction among patients with heart failure and preserved ejection fraction. (2022) European Journal of Heart Failure, DOI: 10.1002/ejhf.2435
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Christersson C, Baron T, Flachskampf F, et al. Screening for Biomarkers Associated with Left Ventricular Function During Follow-up After Acute Coronary Syndrome. (2022) Journal of Cardiovascular Translational Research, DOI: 10.1007/s12265-022-10285-2
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Clark K, Csomor E, Campochiaro C, et al. Integrated analysis of dermal blister fluid proteomics and genome-wide skin gene expression in systemic sclerosis: an observational study. (2022) The Lancet Rheumatology
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Costanzo M, Caterino M, Fedele R, et al. COVIDomics: The Proteomic and Metabolomic Signatures of COVID-19. (2022) International Journal of Molecular Sciences, DOI: 10.3390/ijms23052414
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Cooper LB, Bruce S, Psotka M, et al. Proteomic differences among patients with heart failure taking furosemide or torsemide. (2022) Clinical Cardiology, DOI: 10.1002/clc.23733
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Dahlin M, Singleton SS, David JA, et al. Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet. (2022) EBioMedicine, DOI: 10.1016/j.ebiom.2022.104061
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Dakhel A, Memon AA, Zarrouk M, et al. Novel cardiovascular biomarkers associated with peripheral arterial disease in men screened for abdominal aortic aneurysm. (2022) Vasa, DOI: 10.1024/0301-1526/a000999
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Damsky W, Wang A, Kim DJ, et al. Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis. (2022) Nature Communications, DOI: 0.1038/s41467-022-30615-x
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de Lange I, Petersen TB, de Bakker M, et al. Heart failure subphenotypes based on repeated biomarker measurements are associated with clinical characteristics and adverse events (Bio-SHiFT study). (2022) International Journal of Cardiology, DOI: 10.1016/j.ijcard.2022.06.020
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Ding, Z., Wang, N., Ji, N. et al. Proteomics technologies for cancer liquid biopsies. (2022) Molecular Cancer, DOI: 10.1186/s12943-022-01526-8
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Dlamini SN, Norris SA, Mendham AE, et al. Targeted proteomics of appendicular skeletal muscle mass and handgrip strength in black South Africans: a cross-sectional study. (2022) Scientific Reports, DOI: 10.1038/s41598-022-13548-9
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D’Onofrio V, Heylen D, Pusparum M, et al. A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis. (2022 Journal of Intensive Care, DOI: 10.1186/s40560-022-00602-x
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Dörner T, Tanaka Y, Dow ER, et al. Mechanism of action of baricitinib and identification of biomarkers and key immune pathways in patients with active systemic lupus erythematosus (2022) Annals of the Rheumatic Diseases, DOI: 10.1136/annrheumdis-2022-222335
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Edfors F, Iglesias MJ, Butler L and Odeberg J. Proteomics in thrombosis research. (2022) Research and Practise in Thrombosis and Haemostasis, DOI: 10.1002/rth2.12706
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Fairhurst-Hunter Z, Walters RG, Zink A, et al.  Investigation into the Health Effects of Reduced Chymase Function Using Predicted Loss-of-Function Mutations in CMA1. (2022) Journal of Cardiovascular Translational Research, DOI: 10.1007/s12265-022-10261-w
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Fan Q, Shi J, Yang Y,  et al. Clinical characteristics and immune profile alterations in vaccinated individuals with breakthrough Delta SARS-CoV-2 infections. (2022) Nature Communications, DOI: 10.1038/s41467-022-31693-7
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Feng X, Lawrence MG, Payne SC, et al. Lower viral loads in rhinovirus-challenged allergic subjects despite reduced innate immunity. (2022) Annals of Allergy, Asthma & Immunology, DOI: 10.1016/j.anai.2022.01.007
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Ferreira JP, Verdonschot JAJ, Girerd N,  et al. Influence of ejection fraction on biomarker expression and response to spironolactone in people at risk of heart failure: findings from the HOMAGE trial. (2022) European Journal of Heart Failure, DOI: 10.1002/ejhf.2455
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Ferreira MB, Fonseca T, Costa R, et al. Sex differences in circulating proteins of patients with rheumatoid arthritis: A cohort study. (2022) International Journal of Rheumatic Diseases, DOI: 10.1111/1756-185X.14323
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Gao Y, Cai C, Wullimann D, et al. Immunodeficiency syndromes differentially impact the functional spectrum of SARS-CoV-2-specific T cells elicited by mRNA vaccination. (2022) Immunity, DOI: 10.1016/j.immuni.2022.07.005
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García-Hidalgo MC, González J, Benítez ID, et al. Proteomic profiling of lung diffusion impairment in the recovery stage of SARS-CoV-2-induced ARDS. (2022) Clinical Translational Medicine, DOI: 10.1002/ctm2.838.
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Gawde S, Agasing A, Bhatt N, et al. Biomarker panel increases accuracy for identification of an MS relapse beyond sNfL. (2022) Multiple Sclerosis and Related Disorders, DOI: 10.1016/j.msard.2022.103922
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Gezelius E, Bendahl P-O, Gallo W, et al. Circulating Levels of the Cardiovascular Biomarkers ST2 and Adrenomedullin Predict Outcome within a Randomized Phase III Lung Cancer Trial (RASTEN). (2022) Cancers, DOI: 10.3390/cancers14051307
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Ghanbari F, Yazdanpanah N, Yazdanpanah M, et al. Connecting Genomics and Proteomics to Identify Protein Biomarkers for Adult and Youth-Onset Type 2 Diabetes: A Two-Sample Mendelian Randomization Study. (2022) Diabetes, DOI: 10.2337/db21-1046
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Gilly A, Klaric L, Park YC, et al. Gene-based whole genome sequencing meta-analysis of 250 circulating proteins in three isolated European populations. (2022) Molecular Metabolism, DOI: 10.1016/j.molmet.2022.101509
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Girerd N, Cleland J, Anker SD, et al. Inflammation and remodeling pathways and risk of cardiovascular events in patients with ischemic heart failure and reduced ejection fraction. (2022) Scientific Reports, DOI: 10.1038/s41598-022-12385-0
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Glerup R, Svensson M, Jakobsen LH, et al. Multiplex proteomics as risk predictor of infection in patients treated with hemodialysis-A prospective multicenter study. (2022) Hemodyalisis International, DOI: 10.1111/hdi.12987
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Gorreja F, Caër C, Rush STA, et al. MEFV and NLRP3 Inflammasome Expression Is Attributed to Immature Macrophages and Correlates with Serum Inflammatory Proteins in Crohn´s Disease Patients. (2022) Inflammation, DOI: 10.1007/s10753-022-01647-8
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Gyllensten U, Hedlund-Lindberg J, Svensson J, et al. Next Generation Plasma Proteomics Identifies High-Precision Biomarker Candidates for Ovarian Cancer. (2022) Cancers, DOI: 10.3390/cancers14071757
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Göteson A, Isgren A, Sparding T,  et al. A serum proteomic study of two case-control cohorts identifies novel biomarkers for bipolar disorder. (2022) Translational  Psychiatry, DOI: 10.1038/s41398-022-01819-y
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He B, Huang Z, Huang C, et al. Clinical applications of plasma proteomics and peptidomics: Towards precision medicine. (2022) Proteomics Clinical Applications, DOOI: 10.1002/prca.202100097
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Heath L, Earls J, Magis A, et al. Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90. (2022) Scientific Reports, DOI: 10.1038/s41598-022-09825-2
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Henry A, Gordillo-Maranon M, Finan C, et al. Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization. (2022) Circulation, DOI: 10.1161/CIRCULATIONAHA.121.056663
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Henry N, Frank J, McLouth C, et al. Short Chain Fatty Acids Taken at Time of Thrombectomy in Acute Ischemic Stroke Patients Are Independent of Stroke Severity But Associated With Inflammatory Markers and Worse Symptoms at Discharge. (2022) Frontiers in Immunology, DOI: 10.3389/fimmu.2021.797302
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Hensgens MPM, Delemarre EM, Drylewicz J, et al.  Clinical features and immune-related protein patterns of anti-MDA5 positive clinically amyopathic dermatomyositis Dutch patients. (2022) Rheumatology, DOI: 10.1093/rheumatology/keac030
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Henkens MTHM, van Ommen AM, Remmelzwaal S, et al. The HFA-PEFF score identifies ‘early-HFpEF’ phenogroups associated with distinct biomarker profiles. (2022) ESC Heart Failure, DOI: 10.1002/ehf2.13861
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Hermans MAW, Heeringa JJ, Swagemakers SGA, et al. Altered leukocyte subsets and immune proteome indicate pro-inflammatory mechanisms in mastocytosis. (2022) Journal of Allergy and Clinical Immunology, DOI: 10.1016/j.jaci.2021.12.786
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Heydarian M, Oak P, Zhang X, et al. Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant. (2022) Thorax, DOI: 10.1136/thoraxjnl-2021-218083
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Hinkelbein J, Johnson KVL, Kiselev N, et al. Proteomics-Based Serum Alterations of the Human Protein Expression after Out-of-Hospital Cardiac Arrest: Pilot Study for Prognostication of Survivors vs. Non-Survivors at Day 1 after Return of Spontaneous Circulation (ROSC). (2022) Journal of Clinical Medicine, DOI: 10.3390/jcm11040996
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Ho MF, Zhang C, Moon I, et al. Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism. (2022) Molecular Metabolism, DOI: 10.1016/j.molmet.2022.101534
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Huemer MT, Petera A, Hauk S, et al. Proteomics of the phase angle: Results from the population-based KORA S4 study. (2022) Clinical Nutrition, DOI: 10.1016/j.clnu.2022.06.038
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Huuhtanen J, Bhattacharya D, Lönnberg T, et al. Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia. (2022) Nature Communications, DOI: 10.1038/s41467-022-29173-z
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Jiang R, Smailovic U, Haytural H, et al. Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis. (2022) Acta Neuropathologica Communications, DOI: 10.1186/s40478-022-01398-5
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Johansson M, Ulfenborg B, Andersson CX, et al. Characterization of a Human Stem Cell-Based Model of Cardiac Hypertrophy. (2022) Life, DOI: 10.3390/life12020293
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Jones DEJ, Wetten A, Barron-Millar B, et al. The relationship between disease activity and UDCA response criteria in primary biliary cholangitis: A cohort study. (2022) eBiomedicine, DOI: 10.1016/j.ebiom.2022.104068
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Junus K, Björk Ragnarsdóttir I, et al. Elevated mid-pregnancy plasma levels of angiotensin-converting enzyme in women prior to the development of preeclampsia. (2022) Scientific Reports, DOI: 10.1038/s41598-022-08081-8
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Kartsonaki C, Pang Y, Millwood I, et al. Circulating proteins and risk of pancreatic cancer: a case-subcohort study among Chinese adults. (2022) International Journal of Epidemiology, DOI: 10.1093/ije/dyab274
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Kaye D, Nanayakkara S, Wang B, et al. Characterization of Cardiac Sympathetic Nervous System and Inflammatory Activation in HFpEF Patients. (2022) JACC: Basic to Translational Science, DOI: 10.1016/j.jacbts.2021.11.007
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Khan F, Gonçalves I, Shore AC,  et al. Plaque characteristics and biomarkers predicting regression and progression of carotid atherosclerosis. (2022) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2022.100676
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Khera T, Madsen LW, Du Y, et al. Soluble inflammatory mediators identify HCV patients who may be cured with four weeks of antiviral treatment.. (2022) Journal of Viral Hepatitis, DOI: 10.1111/jvh.13652
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Kierczak M, Rafati N, Höglund J, et al. Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability. (2022) Nature Communications, DOI: 10.1038/s41467-022-30208-8
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Kindt ASD, Förster KM, Cochius-den Otter SCM, et al. Validation of disease-specific biomarkers for the early detection of bronchopulmonary dysplasia. (2022) Pediatric Research, DOI: 10.1038/s41390-022-02093-w
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Kivisäkk P, Magdamo C, Trombetta B, et al. Plasma biomarkers for prognosis of cognitive decline in patients with mild cognitive impairment. (2022) Brain Communications, DOI: 10.1093/braincomms/fcac155
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Klimczak-Tomaniak D, de Bakker M, Bouwens E, et al. Dynamic personalized risk prediction in chronic heart failure patients: a longitudinal, clinical investigation of 92 biomarkers (Bio-SHiFT study). (2022) Scientific Reports, DOI: 10.1038/s41598-022-06698-3
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Klyucherev TO, Olszewski P, Shalimova AA, et al. Advances in the development of new biomarkers for Alzheimer’s disease. (2022) Translational Neurodegeneration, DOI: 10.1186/s40035-022-00296-z
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Kolossváry M, deFilippi C, Lu MT, et al. Proteomic Signature of Subclinical Coronary Artery Disease in People with HIV: Analysis of the REPRIEVE Mechanistic Substudy. (2022) Journal of Infectious Diseases, DOI: 10.1093/infdis/jiac196
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Kopecky J, Pérez JE, Eriksson H, et al. Intratumoral administration of the antisecretory peptide AF16 cures murine gliomas and modulates macrophage functions. (2022) Scientific Reports, DOI: 10.1038/s41598-022-08618-x
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Korduner J, Holm H, Jujic A, et al. Galectin-4 levels in hospitalized versus non-hospitalized subjects with obesity: the Malmö Preventive Project. (2022) Cardiovascular Diabetology, DOI: 10.1186/s12933-022-01559-9.
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Koschitzky M, Navrazhina K, Garshick MS, et al. Ustekinumab reduces serum protein levels associated with cardiovascular risk in psoriasis vulgaris. (2022) Experimental Dermatology, DOI: 10.1111/exd.14582
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Kuan PF, Yang X, Kotov R, et al.  Metabolomics analysis of post-traumatic stress disorder symptoms in World Trade Center responders. (2022) Translational Psychiatry, DOI: 10.1038/s41398-022-01940-y
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Kuijpers Y, Chu X, Jaeger M, et al. The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses. (2022) Frontiers in Immunology, DOI: 0.3389/fimmu.2022.859387
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Kuipers S, Overmars LM, van Es B, et al. A cluster of blood-based protein biomarkers reflecting coagulation relates to the burden of cerebral small vessel disease. (2022) Journal of Cerebral Blood Flow & Metabolism, DOI: 10.1177/0271678X221077339
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Laursen JC, Søndergaard-Heinrich N, Haddock B, et al. Kidney oxygenation, perfusion and blood flow in people with and without type 1 diabetes. (2022) Clinical Kidney Journal, DOI: 10.1093/ckj/sfac145
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Lautenbach MJ, Yman V, Silva CS, et al. Systems analysis shows a role of cytophilic antibodies in shaping innate tolerance to malaria. (2022) Cell Reports, DOI: 10.1016/j.celrep.2022.110709
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Leonetti S, Tricó D, Nesti L, et al. Soluble CD40 receptor is a biomarker of the burden of carotid artery atherosclerosis in subjects at high cardiovascular risk. (2022) Atherosclerosis, DOI: 10.1016/j.atherosclerosis.2022.01.003
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Lind PM, Lind L, Salihovic S, et al.  Serum levels of perfluoroalkyl substances (PFAS) and body composition – A cross-sectional study in a middle-aged population. (2022) Environmental Research, DOI: 10.1016/j.envres.2022.112677
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Lindblad A, Johansson C, Persson K & Demirel I.  The role of caspase-1, caspase-4 and NLRP3 in regulating the host cell response evoked by uropathogenic Escherichia coli. (2022) Scientific Reports, DOI: 10.1038/s41598-022-06052-7
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Linkas J, Ahmed LA, Csifcsak G, et al. Are pro-inflammatory markers associated with psychological distress in a cross-sectional study of healthy adolescents 15-17 years of age? The Fit Futures study. (2022) BMC Psychology, DOI: 10.1186/s40359-022-00779-8
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Linkas J, Ahmed LA, Csifcsak G, et al. C-Reactive Protein and TGF-α Predict Psychological Distress at Two Years of Follow-Up in Healthy Adolescent Boys: The Fit Futures Study. (2022) Frontiers in Psychology, DOI: 10.3389/fpsyg.2022.823420
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Lindkvist M, Zegeye MM, Grenegård M, et al. Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells. (2022) International Journal of Molecular Sciences, DOI:  10.3390/ijms23031448
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Liu J, Wang Y, Tian Z, et al. Multicenter phase II trial of Camrelizumab combined with Apatinib and Eribulin in heavily pretreated patients with advanced triple-negative breast cancer. (2022) Nature Communications, DOI: 10.1038/s41467-022-30569-0
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Ljunggren HG, Ask EH, Cornillet M, et al. The Karolinska KI/K COVID-19 Immune Atlas: An open resource for immunological research and educational purposes. (2022) Scandinavian Journal of Immunology, DOI: 10.1111/sji.13195
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Lötsch J, Mustonen L, Harno H and Kalso E.  Machine-Learning Analysis of Serum Proteomics in Neuropathic Pain after Nerve Injury in Breast Cancer Surgery Points at Chemokine Signaling via SIRT2 Regulation. (2022) International Journal of Molecular Sciences, DOI: 10.3390/ijms23073488
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Löwenmark T, Li X, Löfgren-Burström A, et al. Parvimonas micra is associated with tumour immune profiles in molecular subtypes of colorectal cancer. (2022) Cancer Immunology, Immunotherapy, DOI: 10.1007/s00262-022-03179-4
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Macdonald-Dunlop E, Taba N, Klarić L, et al. A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk. (2022) Aging, DOI: 10.18632/aging.203847
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Maglinger B, McLouth C, Frank J, et al. Influence of BMI on adenosine deaminase and stroke outcomes in mechanical thrombectomy subjects. (2022) Brain, Behavior, & Immunity – Health, DOI: 10.1016/j.bbih.2022.100422
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Maalmi H, Herder C, Huth C, et al. Effect of obesity on the associations of 25-hydroxyvitamin D with prevalent and incident distal sensorimotor polyneuropathy: population-based KORA F4/FF4 study. (2022) International Journal of Obesity, DOI: 10.1038/s41366-022-01122-2
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Mi J, Liu Z, Pei S, et al. Mendelian randomization study for the roles of IL-18 and IL-1 receptor antagonist in the development of inflammatory bowel disease. (2022) International Immunopharmacology, DOI: 10.1016/j.intimp.2022.109020
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Michels JR, Nazrul MS, Adhikari S, et al. Th1, Th2 and Th17 inflammatory pathways synergistically predict cardiometabolic protein expression in serum of COVID-19 patients. (2022) Molecular Omics, DOI: 10.1039/d2mo00055e
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Mickael C, Khetfets V, Langouët-Astrié C, et al. Peripheral Blood Inflammation Profile of Patients with Pulmonary Arterial Hypertension Using the High-Throughput Olink Proteomics Platform. (2022) American Journal of Respiratory Cell and Molecular Biology, DOI: 10.1165/rcmb.2021-0369LE
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Miclescu AA, Granlund P, Butler S, Gordh T. Association between systemic inflammation and experimental pain sensitivity in subjects with pain and painless neuropathy after traumatic nerve injuries. (2022) Scandinavian Journal of Pain, DOI: 10.1515/sjpain-2021-0195
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Morrocchi E, Pighi C, Pascucci GR, et al. Perinatally HIV-infected adolescents and young adults demonstrate distinct BNT162b2 mRNA COVID-19 vaccine immunogenicity. (2022) Clinical Infectious Diseases, DOI: 10.1093/cid/ciac408
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Mukama T, Fortner RT, Katzke V, et al. Prospective evaluation of 92 serum protein biomarkers for early detection of ovarian cancer. (2022) British Journal of Cancer, DOI: 10.1038/s41416-021-01697-z
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Mukherjee A, Pednekar C,  Kolke S, et al. Insights on Proteomics-Driven Body Fluid-Based Biomarkers of Cervical Cancer. (2022) Proteomes, DOI: 10.3390/proteomes10020013
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Nahi H, Chrobok M, Meinke S, et al. Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma. (2022) Cell Reports Medicine, DOI: 10.1016/j.xcrm.2022.100508
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Naing A, Powderly JD, Nemunaitis JJ, et al. Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study. (2022) Journal of Immunotherapy for Cancer, DOI: 10.1136/jitc-2021-004223
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Navrazhina K, Frew JW, Grand D, et al. IL-17RA blockade by brodalumab decreases inflammatory pathways in hidradenitis suppurativa skin and serum.  (2022) British Journal of Dermatology, DOI: 10.1111/bjd.21060
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Nayar S, Pontarini E, Campos J, et al. Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL. (2022) Communications Biology, DOI: 10.1038/s42003-022-03344-6
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Nieraad H, de Bruin N, Arne O, et al. The Roles of Long-Term Hyperhomocysteinemia and Micronutrient Supplementation in the AppNL–G–F Model of Alzheimer’s Disease. (2022) Frontiers in Aging Neuroscience, DOI: 10.3389/fnagi.2022.876826
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Nilsson AK, Rydbeck H, Thorsell A, et al. The proteome signature of cord blood plasma with high hematopoietic stem and progenitor cell count. (2022) Stem Cell Research, DOI: 10.1016/j.scr.2022.102752
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Niroomand A, Ghaidan H, Hallgren O, et al. Corticotropin releasing hormone as an identifier of bronchiolitis obliterans syndrome. (2022) Scientific Reports, DOI: 10.1038/s41598-022-12546-1
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Nurmohamed NS, Belo Pereira JP, et al. Targeted proteomics improves cardiovascular risk prediction in secondary prevention. (2022) European Heart Journal, DOI: 10.1093/eurheartj/ehac055
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Nguyen TTL, Wang M, Liu D, et al. Proteomic Biomarkers of Sacubitril/Valsartan Treatment Response in Heart Failure With Preserved Ejection Fraction: Molecular Insights Into Sex Differences. (2022) Circulation Heart Failure, DOI: 10.1161/CIRCHEARTFAILURE.122.009629
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Kragstrup T, Adams M, Lomholt S, Nielsen M, Heftdal L, Schafer P and Deleuran B. IL-12/IL-23p40 identified as a downstream target of apremilast in ex vivo models of arthritis. (2019) Therapeutic Advances in Musculoskeletal Disease, doi.org/10.1177/1759720X19828669
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Lind L, Figarska S, Sundström J, Fall T, Ärnlöv J and Inglesson E. Changes in Proteomic Profiles are Related to Changes in BMI and Fat Distribution During 10 Years of Aging. (2019) Obesity, DOI: 10.1002/oby.22660
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Lindahl G, Abrahamsson A and Dabrosin C. Dietary flaxseed and tamoxifen affect the inflammatory microenvironment in vivo in normal human breast tissue of postmenopausal women. (2019) European Journal of Clinical Nutrition, doi: 10.1038/s41430-019-0396-y
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McGilligan V, Watterson S, Rjoob K, Chemaly M, Bond R, Iftikhar A, Knoery C, Leslie S, McShane A, Bjourson A and Peace A. An exploratory analysis investigating blood protein biomarkers to augment ECG diagnosis of ACS (2019) Journal of Electrocardiology, doi: 10.1016/j.jelectrocard.2019.09.002
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Memon A, Zarrouk M, Ågren-Witteschus S, Sundquist J, Gottsäter A and Sundquist K. Identification of novel diagnostic and prognostic biomarkers for abdominal aortic aneurysm (2019) European Journal of Preventive Cardiology, doi: 10.1177/2047487319873062
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Muhammad I, Borné Y, Bao X, Melander O, Orho-Melander M, Nilsson P, Nilsson J and Engström G. Circulating HER2/ErbB2 Levels Are Associated With Increased Incidence of Diabetes: A Population-Based Cohort Study. (2019) Diabetes Care, doi: 10.2337/dc18-2556
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Muinau T, Prasanna H Boruah H and  Pal M. Multi-biomarker panel signature as the key to diagnosis of ovarian cancer. (2019) Heliyon, DOI: 10.1016/j.heliyon.2019.e02826
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Nixon A, Schalper K, Jacobs I, Potluri S, Wang I-M and Fleener C. Peripheral immune-based biomarkers in cancer immunotherapy: can we realize their predictive potential? (2019) Journal for Immunotherapy of Cancer, DOI: 10.1186/s40425-019-0799-2
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Offer S, Menard J, Enríquez Pérez J, de Oliveira K, Chandran V, Johansson M, Bång-Rudenstam A,  Siesjö P, Ebbesson A, Hedenfalk I, Sundgren P, Darabi A and Belting M. Extracellular lipid loading augments hypoxic paracrine signaling and promotes glioma angiogenesis and macrophage infiltration. (2019) Journal of Experimental & Clinical Cancer Research, doi: 10.1186/s13046-019-1228-6
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Pavel A, Zjou L, Diaz A, Ungar B, Dan J, He H, Estrada Y, Xu H, Fernades M, Renert-Yuval, Krueger J and Guttman-Yassky E. The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature (2019) Journal of the American Association of Dermatology, doi: 10.1016/j.jaad.2019.10.039
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Pulliam L, Sun B, Mustapic M, Chawla S and Kapogiannis D. Plasma neuronal exosomes serve as biomarkers of cognitive impairment in HIV infection and Alzheimer’s disease. (2019) Journal of NeuroVirology,  doi: 10.1007/s13365-018-0695-4
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Raijmakers R, Koeken V, Jansen A, Keijmel S, Roerink M, Joosten L, Netea M, van der Meer J and Bleeker-Rovers C. Cytokine profiles in patients with Q fever fatigue syndrome. (2019) Journal of Infection, doi.org/10.1016/j.jinf.2019.01.006
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Ravi D, Sarkar S, Purvey S, Passero F, Beheshti A, Chen Y, Mokhtar M, David K, Konry T and Evens A. Interaction kinetics with transcriptomic and secretory responses of CD19-CAR natural killer-cell therapy in CD20 resistant non-hodgkin lymphoma. (2019) Leukemia, DOI: 10.1038/s41375-019-0663-x
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van der Zwan M, Hesselink D, Clahsen-van Groningen M and Baan C. Targeted proteomic analysis detects acute T cell-mediated kidney allograft rejection in belatacept-treated patients. (2019) Therapeutic Drug Monitoring, doi: 10.1097/FTD.0000000000000587
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Wang H, Davison M, Wang K, Xia T-H, Kramer M, Call K, Luo J, Wu X, Zuccarino R, Bacon C, Bai Y, Moran J, Gutmann L, Feely S, Grider T, Rossor A, Reilly M, Svaren J and Shy M. Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A. (2019) Annals of Clinical & Translational Neurology, DOI: 10.1002/acn3.50965
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Whelan C, Mattsson N, Nagle M, Vijayaraghavan S, Hyde C, Janelidze S, Stomrud E, Lee J, Fitz L, Samad T, Ramaswamy G, Margolin R, Mälarstig A and Hansson O. Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer’s disease. (2019) Acta Neuropathologica Communications, DOI: 10.1186/s40478-019-0795-2
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Wiberg A, Olsson-Strömberg U, Herman S, Kultima K and Burman J. Profound but Transient Changes in the Inflammatory Milieu of the Blood During Autologous Hematopoietic Stem Cell Transplantation. (2019) Biology of Blood and Marrow Transplantation, DOI: 10.1016/j.bbmt.2019.09.010
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Wierenga A, Cao J, Mouthaan H, van Weeghel C, Verdijk R, van Duinen S, Kroes W, Dogrusöz M, Marinkovic M, van der Burg S, Luyten G and Jager M. Aqueous Humor Biomarkers Identify Three Prognostic Groups in Uveal Melanoma. (2019) Investigative Ophthalmology & Visual Science, DOI: 10.1167/iovs.19-28309
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Zamaratskaia G, Omar NAM, Brunius C, Hallmans G, Johansson J-E, Andersson S-O, Larsson A, Åman P. and Landberg R. Consumption of whole grain/bran rye instead of refined wheat decrease concentrations of TNF-R2, e-selectin, and endostatin in an exploratory study in men with prostate cancer. (2019) Clinical Nutrition, doi.org/10.1016/j.clnu.2019.01.007
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Zheng J, Maerz W, Gergei I et. al. Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures. (2019) Journal of Bone and Mineral Research, DOI: 10.1002/jbmr.3803
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Abrahamsson A, Rzepecka A and Dabrosin C. Equal Pro-inflammatory Profiles of CCLs, CXCLs, and Matrix Metalloproteinases in the Extracellular Microenvironment In Vivo in Human Dense Breast Tissue and Breast Cancer. (2018) Frontiers in Immunology, doi: 10.3389/fimmu.2017.01994
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Al-Talabany S, Mordi I, Houston G, Colhoun H, Weir-McCall J, Matthew S, Looker H, Levin D, Belch J, Dove F, Khan F and Lang C. Epicardial adipose tissue is related to arterial stiffness and inflammation in patients with cardiovascular disease and type 2 diabetes. (2018) BMC Cardiovascular Disorders, doi.org/10.1186/s12872-018-0770-z
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Aqrawi L, Ivanchenko M, Björk A, Ramírez Sepúlveda J, Imgenberg-Kreuz J, Kvarnström M, Haselmayer P, Jensen J, Nordmark G, Chemin K, Skarstein G and Wahren-Herlenius M. Diminished CXCR5 expression in peripheral blood of patients with Sjögren’s syndrome may relate to both genotype and salivary gland homing. (2018) Clinical & Experimental  Immunology, doi: 10.1111/cei.13118
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Arrigo M, Vodovar N,Von Moos S, Masson E, Segerer S, Cippà P and Mebazaa A. High accuracy of proximity extension assay technology for the quantification of plasma brain natriuretic peptide. (2018) Journal of  Clinical Laboratory Analysis, doi.org/10.1002/jcla.22574
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Bao X, Borné Y, Faqir Muhammad I, Nilsson J, Lind L, Melander O, Niu K, Orho-Melander M and Engström G. Growth differentiation factor 15 is positively associated with incidence of diabetes mellitus: the Malmö Diet and Cancer–Cardiovascular Cohort (2018)  Diabetologia, DOI/10.1007/s00125-018-4751-7
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Barriuso J, Custodio A, Afonso R, Alonso V, Astudillo A, Capdevila J, Carbonero R, Grande E, Jimenez-Fonseca P, Marazuela M, Rodríguez-Antona C and Aller Y. Prognostic and predictive biomarkers for somatostatin analogs, peptide receptor radionuclide therapy and serotonin pathway targets in neuroendocrine tumours. (2018) Cancer Treatment Reviews, doi.org/10.1016/j.ctrv.2018.09.00
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Berntsson J, Smith G, Johnson L, Söderholm M, Borné Y, Melander O, Orho-Melander M, Nilsson J and Engström G. Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke. (2018) Heart, doi:10.1136/heartjnl-2018-313684
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Bhandage A, Jin Z, Korol S, Shenb Q, Pe Y, Deng Q, Espes D, Carlsson P-O, Kamali-Moghaddamb M and Birnir B. GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes. (2018) EBioMedicine, doi.org/10.1016/j.ebiom.2018.03.019
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Birgirsson H, Tsimogiannis K, Freyhult E and Kamali-Moghaddam M. Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer. (2018) Translational Oncology, doi:/10.1016/j.tranon.2018.05.012
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Vossen A, van der Zee1 H, Davelaar N, Mus A, van Doorn M and Prens E. Apremilast for moderate hidradenitis suppurativa: no significant change in lesional skin inflammatory biomarkers. (2018) Journal of the European Academy of Dermatology and Venereology, doi.org/10.1111/jdv.15354
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Vroegindewey M, Oemrawsingh R, Kardys I, Asselbergs F, van der Harst P, Oude Ophuis A, Cramer G, Maas A, Hong Kie The S, Wardeh A, Mouthaan H, Boersma E and Akkerhuis M. The temporal pattern of immune and inflammatory proteins prior to a recurrent coronary event in post-acute coronary syndrome patients. (2018) Biomarkers, doi: 10.1080/1354750X.2018.1539768
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Wigren M, Svenugnsson E, Yao Mattisson I, Gustafsson J, Gunnarsson I, Zickert A, Elvin K, Jensen-Urstad K, Bengtsson A, Gullstrand B, Nordin Fredrikson G and Nilsson J. Cardiovascular disease in systemic lupus erythematosus is associated with increased levels of biomarkers reflecting receptor-activated apoptosis (2018) Atherosclerosis, doi: 10.1016/j.atherosclerosis.2018.01.022
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Yeung V, Webber J, Dunlop E, Morgan H, Hutton J, Gurney M, Jones E, Falcon-Perez J, Tabi Z, Errington R and Clayton A. Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma (2018) Nanoscale, doi/10.1039/C8NR02417K
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Zhernakova D, Le T, Kurilshikov A, Atanasovska B, Bonder M, Sanna S, Claringbould A, Võsa U, Deelen P, LifeLines cohort study, BIOS consortium, Franke L, de Boer R, Kuipers F, Netea M, Hofker M, Wijmenga C, Zhernakova A and Fu J. Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome. (2018) Nature Genetics, doi.org/10.1038/s41588-018-0224-7
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2017

Ahsan M, Ek W, Rask-Andersen M, Karlsson T, Lind-Thomsen A, Enroth S, Gyllensten U and Johansson Å. The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases. (2017) PLOS Genetics, DOI: 10.1371/journal.pgen.1007005
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Andersson E, Bergemalm D, Kruse R, Neumann G, D’Amato M, Repsilber D, and Halfvarson J. Subphenotypes of inflammatory bowel disease are characterized by specific serum protein profiles. (2017) PLOS One, doi.org/10.1371/journal.pone.0186142
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Bayes-Genis A, Núñez J, Zannad F, Ferreira J, Anker S, Cleland J, Dickstein K, Filippatos G, Lang C, Ng L, Ponikowski P, Samani N, van Veldhuisen D, , Zwinderman A, Metra M, Lupón J and Voors A. The PCSK9-LDL Receptor Axis (2017) J. Am. College Cardiology, doi: 10.1016/j.jacc.2017.08.057
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Bergthorsdottir R, Ragnarsson O, Skrtic S, Glad K, Nilsson S, Louis Ross I, Leonsson-Zachrisson M and Johannsson G. Visceral Fat and Novel Biomarkers of Cardiovascular Disease in Patients with Addison’s Disease; a case-control study (2017) The Journal of Clinical Endocrinology & Metabolism, doi.org/10.1210/jc.2017-01324
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Bhargava M, Viken K, Wang Q, Jagtap P, Bitterman P, Ingbar D and Wendt C. Bronchoalveolar Lavage Fluid Protein Expression in Acute Respiratory Distress Syndrome. (2017) Scientific Reports, DOI:10.1038/s41598-017-07791-8
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Björkbacka H, Yao Mattisson I, Wigren M, Melander O, Fredrikson G, Bengtsson E, Gonçalves I, Almgren P, Lagerstedt J, Orho-Melander M, Engström G and Nilsson J. Plasma stem cell factor levels are associated with risk of cardiovascular disease and death. (2017) Journal of Internal Medicine, doi/10.1111/joim.12675
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Björkesten J, Enroth S, Shen Q, Wik L, Hougaard D, Cohen A, Sörensen L, Giedraitis V, ingelsson M, Larsson A, Kamali-Moghaddam M and Landegren U. Stability of Proteins in Dried Blood Spot Biobanks (2017) Molecular & Cellular Proteomics, doi: 10.1074/mcp.RA117.000015
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Boldrup L,Troiano G,Gu X, Coates P,Fåhraeus R, Wilms T, Norberg-Spaak L, Wang L and Nylander K. Evidence that circulating proteins are more promising than miRNAs for identification of patients with squamous cell carcinoma of the tongue. (2017) Oncotarget, doi:10.18632/oncotarget.21402
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Boylan K, Geschwind K, Koopmeiners J, Geller M, Starr T and Skubitz A. A multiplex platform for the identification of ovarian cancer biomarkers (2017) Clinical Proteomics, DOI 10.1186/s12014-017-9169-6
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Brodin P & Davis M. Human immune system variation (2017), Nat. Rev. Immunol, 17, 21-29
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Brunner P, Suárez-Fariñas M, He H, Malik K, Wen H-C, Gonzalez J, Chan T, Estrada Y, Zheng X, Khattri S, Dattola N, Krueger J and Guttman-Yassky E. The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins. (2017) Scientific Reports, DOI:10.1038/s41598-017-09207-z
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Bryan R, Gordon N, Abbotts B, Zeegers M, Cheng K, James N and  Ward D. Multiplex screening of 422 candidate serum biomarkers in bladder cancer patients identifies syndecan-1 and macrophage colony stimulating factor 1 as prognostic indicators. (2017) Translational Cancer Research, doi:10.21037/tcr.2017.04.19
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Bränn E, Papadopoulos F, Fransson E, White R, Edvinsson Å, Hellgren C, Kamali-Moghaddam M, Boström A, Schiöth H, Sundström-Poromaa H and Skalkidou A. Inflammatory markers in late pregnancy in association withpostpartum depression—A nested case-control study (2017) Psychoneuroendocrinology, doi.org/10.1016/j.psyneuen.2017.02.029
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Bäckryd E, Lind A-L, Thulin M,  Larsson A, Gerdle B and Gordh T. High levels of cerebrospinal fluid chemokines point to the presence of neuroinflammation in peripheral neuropathic pain: a cross-sectional study of 2 cohorts of patients compared with healthy controls. (2017) Pain, doi:10.1097/j.pain.0000000000001061
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Bäckryd E, Tanum L, Lind A-L, Larsson A and Gordh T. Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. (2017) Journal of Pain Research, https://doi.org/10.2147/JPR.S128508
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Carlsson A,Ingelsson E, Sundström J, Carrero J, Gustafsson S, Feldreich T, Stenemo M, Larsson A, Lind L and Ämlöv J. Use of Proteomics To Investigate Kidney Function Decline over 5 Years. Clinical Journal of the American Society of Nephrology (2017), doi: 10.2215/CJN.08780816
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Chen H, Qian J, Werner S, Cuk K, Knebel P and Brenner H. Development and validation of a panel of five proteins as blood biomarkers for early detection of colorectal cancer. (2017) Clinical Epidemiology, doi: 10.2147/CLEP.S144171
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Cornelis M,   Gustafsson S,  Ärnlöv J, Elmståhl S, Söderberg S,  Sundström J,   Michaëlsson K,  Lind L and Ingelsson E. Targeted proteomic analysis of habitual coffee consumption. (2017) Journal of Internal Medicine, doi.org/10.1111/joim.12703
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Cowley C, Owen A, Shiels S, Millar J,  Woolley R, Ives N, Osman H, Moss P and Bion J. Safety and Efficacy of Antiviral Therapy for Prevention of Cytomegalovirus Reactivation in Immunocompetent Critically Ill Patients.  (2017) JAMA Internal Medicine, doi:10.1001/jamainternmed.2017.0895
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deFilippi C and Seliger S. A Multibiomarker Approach to Heart Failure Prognostication : A Work in Progress (2017) JACC: Heart Failure, doi.org/10.1016/j.jchf.2017.02.019 [editorial]
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Dencker M, Björgell O and Hlebowicz J. Effect of food intake on 92 neurological biomarkers in plasma. (2017) Brain and Behaviour, DOI: 10.1002/brb3.747.
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Dencker M, Danielson A, Karlsson M, Wollmer P, Andersen L and Thorsson O. Total body fat, abdominal fat, body fat distribution and surrogate markers for health related to adipocyte fatty acid-binding protein (FABP4) in children. (2017) Journal of Pediatric Endocrinology and Metabolism, https://doi.org/10.1515/jpem-2016-0278.
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Dencker M, Gårdinger Y, Björgell O, and Hlebowicz J. Effect of food intake on 92 biomarkers for cardiovascular disease (2017) PLOS One, doi.org/10.1371/journal.pone.0178656
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Drum C, Tan W, Chan S-P, Pakkiri L, Chong J, Liew O-W, Ng T-P, Ling L-H,  Sim D, Leong K-T, Yeo D, Ong H-Y,  Jaufeerally F, Wong R, Chai P, Low A, Davidsson P, Liljeblad M, Söderling A-S, Gan L-M, Bhat R, Purnamawati K, Lam C and Richards M. Thymosin Beta‐4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction (2017) Journal of the American Heart Association, doi.org/10.1161/JAHA.117.005586
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Eriksson E, Milenova I, Wenthe J, Stahle M, Leja-Jarblad J, Ullenhag G, Dimberg A, Moreno R, Alemany R and Loskog A. (2017) Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus. Clinical Cancer Research, Doi: 10.1158/1078-0432.CCR-17-0285
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Flintholm Raft K, Frestad D, Michelsen M, Suhrs H, Rask A, Nilsson M, Hermann T and Prescott E. Peripheral Endothelial Function and Coronary Flow Velocity Reserve Are Not Associated in Women with Angina and No Obstructive Coronary Artery Disease: The iPOWER Study (2017) Journal of Vascular Research, doi.org/10.1159/000479374
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Folkersen L, Fauman E, Sabater-Lleal M, Strawbridge R, Frånberg M, Sennblad B, Baldassarre D, Veglia F, Humphries S, Rauramaa R, de Faire U, Smit A, Giral P, Kurl S, Mannarino E, Enroth S, Johansson Å, Bosdotter Enroth S, Gustafsson S, Lind L, Lindgren C, Morris A, Giedraitis V, Silveira A, Franco-Cereceda A, Tremoli E, IMPROVE study group , Gyllensten U, Ingelsson E, Brunak S, Eriksson P, Ziemek D, Hamsten A and Mälarstig A. Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. (2017) PLOS Genetics 13(4), doi.org/10.1371/journal.pgen.1006706
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Gerdle B, Ghafouri B, Ghafouri N, Bäckryd E and Gordh T. Signs of ongoing inflammation in female patients with chronic widespread pain. A multivariate, explorative, cross-sectional study of blood samples. (2017) Medicine, http://dx.doi.org/10.1097/MD.0000000000006130
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Gohar A, Gonçalves I, Vrijenhoek J, Haitjema S, van Koeverden I, Nilsson J, de Borst G, de Vries J-P, Pasterkamp G, den Ruijter H, Björkbacka H and de Jager S. Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis (2017) International Journal of Cardiology, http://dx.doi.org/10.1016/j.ijcard.2017.03.101
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Hage C, Michaëlsson E, Linde C, Donal E, Daubert J-C, Gan L-M and Lund L. Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction. (2017) Circulation: Cardiovascular Genetics, doi.org/10.1161/CIRCGENETICS.116.001633
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Harlid S, Myte R and Van Guelpen B. The Metabolic Syndrome, Inflammation, and Colorectal Cancer Risk: An Evaluation of Large Panels of Plasma Protein Markers Using Repeated, Prediagnostic Samples. (2017) Mediators of Inflammation, doi:10.1155/2017/4803156
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Hill L, Di Pietro V, Hazeldine J, Davies D, Tomman E, Logan A and Belli A. Cystatin D (CST5): An ultraearly inflammatory biomarker of traumatic brain injury. (2017)  Scientific Reports, DOI:10.1038/s41598-017-04722-5
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Hofmann R, Tornvall P, Witt N, Alfredsson J, Svensson L, Jonasson L and Nilsson L. Supplemental oxygen therapy does not affect the systemic inflammatory response to acute myocardial infarction (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12716
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Jónsdóttir B, Jaworowski Å, San Miguel C and Melander O. IL-8 predicts early mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation (2017) BMC Pulmonary Medicine, DOI: 10.1186/s12890-017-0377-7
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Kim J, Tomalin L, Lee J, Fitz L, Berstein G, Correa-da Rosa J, Garcet S, Lowes M, Valdez H, Wolk R, Suarez-Farinas M and Krueger J. Reduction of inflammatory and cardiovascular proteins in the blood of psoriasis patients; differential responses between tofacitinib and etanercept after 4 weeks of treatment. (2017) Journal of Investigative Dermatology, doi:10.1016/j.jid.2017.08.040A
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Kupcova Skalnikova H, Cizkova J, Cervenka J and Vodicka P. Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research (2017) Int. J. Mol. Sci., doi:10.3390/ijms18122697
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Lakshmikanth T, Olin A, Chen Y, Mikes J, Fredlund E, Remberger M, Omazic B and Brodin P. Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation (2017) Cell Reports, doi.org/10.1016/j.celrep.2017.08.021
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Langley S, Willeit K, Didangelos A, Perisic Matic L, Skroblin P, Barallobre-Barreiro J, Lengquist MN, Rungger G,Kapustin A, Kedenko L, Molenaar C, Lu R, Barwari T, Suna G, Yin X, Iglseder B,Paulweber B, Willeit P, Shalhoub J, Pasterkamp G,Davies A, Monaco C, Hedin U, Shanahan C, Willeit J, Kiechl S and Mayr M. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques. (2017) Journal of  Clinical Investigation, doi:10.1172/JCI86924
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Larssen P, Wik L, Czarnewski P, Eldh M, Lof L, Ronquist J, Dubois L, Freyhult E, Gallant C, Oelrich J, Larsson A, Ronquist G, Villablanca E, Landegren U, Gabrielsson S and Kamali-Moghaddam M. Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay (2017) Molecular & Cellular Proteomics, doi: 10.1074/mcp.M116.064725
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Mahdessian H, Perisic Matic L, Lengquist M, Gertow K, Sennblad B, Baldassarre D, Veglia F, Humphries S, Rauramaa R, de Faire U, Smit A, Giral P, Kurl S, Mannarino E, Tremoli E, Hamsten A, Eriksson P, Hedin U, Mälarstig A, IMPROVE study group. Integrative Studies Implicate Matrix Metalloproteinase 12 as a Culprit Gene for Large-Artery Atherosclerotic Stroke. (2017) Journal of Internal Medicine, DOI: 10.1111/joim.12655
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Mazurkiewicz M, Hillert E-K, Wang X, Pellegrini P, Hägg Olofsson M, Selvaraju K, D’Arcy P and Linder S. Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition. (2017) Oncotarget, doi: 10.18632/oncotarget.15501
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Mohammad M, Noc N, Lang I, Holzer M, Clemmensen P, Jensen U, Metzler B and Erlinge, D. Proteomics in Hypothermia as Adjunctive Therapy in Patients with ST-Segment Elevation Myocardial Infarction: A CHILL-MI Substudy (2017) Therapeutic Hypothermia and Temperature Management, doi.org/10.1089/ther.2016.0041
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Molin C, Westerberg E and Rostedt Punga A. Profile of upregulated inflammatory proteins in sera of Myasthenia Gravis patients (2017) Scientific Reports, doi:10.1038/srep39716.
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Mrazek F, Schneiderova P, Kriegova E, Raida L, Kuba A, Gajdos P, KönigovaJana N, Onderkova J and Ambruzova Z. Profile of Inflammation-Associated Proteins in Early Post-Transplant Samples of Patients After Allogeneic Hematopoietic Stem Cell Transplantation: a Preliminary Study. (2017) Archivum Immunologiae et Therapiae Experimentalis, DOI: 10.1007/s00005-016-0446-2.
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Panezai J, Ghaffar A, Altamash M, Sundqvist K-G, Engström P-E and Larsson A. Correlation of serum cytokines, chemokines, growth factors and enzymes with periodontal disease parameters. (2017) PLOS ONE, doi.org/10.1371/journal.pone.0188945
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Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum J, Alexander V, Willeit J, Kiech S and Mayr M. Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III (2017) Journal of the American College of Cardiology, Vol 69 (7) DOI: 10.1016/j.jacc.2016.11.065 (Online Appendix)
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Petrackova A, Smrzova A, Gajdos P, Schubertova M, Schneiderova P, Kromer P, Snasel V, Skacelova M, Mrazek F, Zadrazil J, Horak P and Kriegova E. Serum protein pattern associated with organ damage and lupus nephritis in systemic lupus erythematosus revealed by PEA immunoassay. (2017) Clinical Proteomics, DOI: 10.1186/s12014-017-9167-8
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Price N, Magis A, Earls J, Glusman G, Levy R, Lausted C, McDonald D, Kusebauch U, Moss C, Zhou Y, Qin S, Moritz R, Brogaard K, Omenn G, Lovejoy J and Hood L. A wellness study of 108 individuals using personal, dense, dynamic data clouds. (2017) Nature Biotechnology, doi:10.1038/nbt.3870
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Roerink M, Knoop H, Bronkhorst E, Mouthaan H, Luuk Hawinkels J, Joosten L and van der Meer J. Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment. (2017) Journal of Translational Medicine, doi: 10.1186/s12967-017-1371-9
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Savola P, Brück O, Olson T, Kelkka T, Kauppi M, Kovanen P, Kytölä S, Sokka-Isler T, Loughran T, Leirisalo-Repo M and Mustjoki S. Somatic STAT3 mutations in the Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia. (2017) Haematologica, doi:10.3324/haematol.2017.175729
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Schiza A, Wenthe J, Mangsbo S, Eriksson E, Nilsson A, Tötterman T, Loskog A and Ulenhag G. Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients. (2017) Journal of Translational Medicine, DOI: 10.1186/s12967-017-1182-z
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Schwenk J, Omenn G, Sun Z, Campbell D, Baker M, Overall C, Aebersold R, Moritz R and Deutsch E. The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays (2017) Journal of Proteome Research, doi:10.1021/acs.jproteome.7b00467
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Shen Q, Björkesten J, Galli J, Ekman D, Broberg J, Nordberg N, Tillander A, Kamali-Moghaddam M, Tybring G and Landegren U. Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays. (2017) Clinical Chemistry and Laboratory Medicine, doi: 10.1515/cclm-2017-0648
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Skau E, Henriksen E, Wagner P, Hedberg P, Siegbahn A and Leppert J. GDF-15 and TRAIL-R2 are powerful predictors of long-term mortality in patients with acute myocardial infarction (2017) European Journal of Preventive Cardiology, doi.org/10.1177/2047487317725017
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Smith G and Gerszten R. Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease (2017) Circulation, doi.org/10.1161/CIRCULATIONAHA.116.025446
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Solheim N, Östlund, S, Gordh T and Rosseland L.A. Women report higher pain intensity at a lower level of inflammation after knee surgery compared with men. (2017) Pain Reports, doi: 10.1097/PR9.0000000000000595
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Stenemo M, Nowak C, Byberg L, Sundström J, Giedraitis V, Lind L, Ingelsson E, Fall T and Ärnlöv J. Circulating proteins as predictors of incident heart failure in the elderly (2017) European Journal of Heart Failure, doi: 10.1002/ejhf.980
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Stensson N, Ghafouri B, Gerdle B and Ghafouri N. Alterations of anti-inflammatory lipids in plasma from women with chronic widespread pain – a case control study (2017) Lipids in Health &  Disease, DOI: 10.1186/s12944-017-0505-7
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Sukma Dewi I, Gidlöf O, Hollander Z, Lam K, Benson M, Braun O, Nilsson J, Tebbutt S, Ng R,  Öhman J, McManus B and Smith G. Immunological Serum Protein Profiles for Noninvasive Detection of Acute Cellular Rejection After Heart Transplantation. (2017) Journal of the American College of Cardiology, doi.org/10.1016/j.jacc.2017.10.012
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Uderhardt S, Ackermann J, Fillep T, Hammond V, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner K, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz‑Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins P, Schabbauer G, Mackman N, Voehringer D, Nadler J, Lee J, Massberg S, Rauh M, Kiechl S, Schett G, O’Donnell V and Krönke G. Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. JEM (2017), doi.org/10.1084/jem.20161070
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Vallejo J,Dunér P, Fredrikson G, Nilsson J and Bengtsson E. Autoantibodies against aldehyde-modified collagen type IV are associated with risk of development of myocardial infarction. (2017) Journal of Internal Medicine, doi/10.1111/joim.12659/full
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Villani A-C, Satija1 R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager P, Rozenblatt-Rosen O, Lane A, Haniffa M, Regev A and Hacohen N. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. (2017) Science, DOI: 10.1126/science.aah4573
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West N, Corrigan J, Owen R, Hoole S, Brown A, Blatcher S and Newby, A. Percutaneous Sampling of Local Biomolecule Gradients Across Coronary Artery Atherosclerotic Plaques.(2017) JACC: Basic to Translational Science, doi: 10.1016/j.jacbts.2017.07.007
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Willeit K, Pechlaner R, Willeit P, Skroblin P, Paulweber B, Schernthaner C, Toell T, Egger G, Weger S, Oberhollenzer M, Kedenko L, Iglseder B, Bonora E, Schett G, Mayr M, Willeit J and Kiechl S. Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation. JAMA Cardiology (2017), doi:10.1001/jamacardio.2017.0064
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Yao Mattisson I, Björkbacka H, Wigren H, Edsfeldt A, Melander O, Nordin Fredrikson G, Bengtsson E, Gonçalves I, Orho-Melander M, Engström G, Almgren P and Nilsson J. Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease. (2017) EBioMedicine, doi.org/10.1016/j.ebiom.2017.11.023
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Yeh C, Adusumilli R, Kullolli M, Mallick P, John E and Pitteri S. Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer. (2017) Biomarker Research, DOI 10.1186/s40364-017-0110-y
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Zhang W, Ambikan A, Sperk M, van Domselaar R, Nowak P, Noyan K, Russom A,, Sönnerborg A and Neogi U. Transcriptomics and Targeted Proteomics Analysis to Gain  Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers. (2017) EBioMedicine, doi:10.1016/j.ebiom.2017.11.031
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Zwicker S, Lira-Junior R, Höög C, Almer S and Boström E. Systemic Chemokine Levels with “Gut-Specific” Vedolizumab in Patients with Inflammatory Bowel Disease—A Pilot Study (2017) International Journal of Molecular Sciences, doi: 10.3390/ijms18081827
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2016

Andreasson U, Blennow K and Zetterberg H. Update on ultrasensitive technologies to facilitate research on blood biomarkers for central nervous system disorders. Alzheimer’s & Dementia (2016), 3, 98-102.
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Berggrund M, Ekman D, Gustavsson I, Sundfeldt K, Olovsson M, Enroth S and Gyllensten U. Protein Detection Using the Multiplexed Proximity Extension Assay (PEA) from Plasma and Vaginal Fluid Applied to the Indicating FTA Elute Micro Card. J. Circ. Biomark. (2016), 5:9. doi:10.5772/64000
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Berntson L, Hedlund-Treutiger I and Alving K. Anti-inflammatory effect of exclusive enteral nutrition in patients with juvenile idiopathic arthritis. (2016) Clinical and Experimental Rheumatology, 34(5):941-945
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Carlsson A, Sundström J, Carrero J, Gustafsson S, Stenemo M, Larsson A, Lind L and Ärnlöv J. Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria. (2016) Eur J. Prev. Cardiol., DOI: 10.1177/2047487316676134.
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Chen H, Knebel P and Brenner H. Empirical evaluation demonstrated importance of validating biomarkers for early detection of cancer in screening settings to limit the number of false-positive findings. (2016) Journal Clinical Epidemiology, doi.org/10.1016/j.jclinepi.2016.01.022
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Darmanis S, Gallant C, Marinescu V,  Niklasson M, Segerman A,  Flamourakis G,  Fredriksson S, Assarsson E, Lundberg M, Nelander S, Westermark B and  Landegren U. Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells. (2016) Cell Reports 14, 380-389.
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Edsfeldt A, Bengtsson E, Asciutto G, Dunér P, Björkbacka H, Fredrikson G.N, Nilsson J, Goncalves I. High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy. Cerebrovasc Dis. (2016); 41:199-203
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Edfeldt K, Daskalakis K, Bäcklin C, Norlén O, Tiensuu Janson E, Westin G, Hellman P and Stålberg P. DcR3, TFF3 and Midkine are Novel Serum Biomarkers in Small Intestinal Neuroendocrine Tumors. (2016) Neuroendocrinology, DOI: 10.1159/000452891
PubMed link>

Eisenberg T. et. al. Cardioprotection and lifespan extension by the natural polyamine spermidine (2016) Nature Medicine, DOI: 10.1038/nm.4222.
PubMed link>

Enroth S, Hallmans G, Grankvist K and Gyllensten, U. (2016) Effects of long-term storage time and original sampling month on biobank plasma protein concentrations. EBioMedicine, 201608.038
Article link >

Genshaft A, Li S, Gallant C, Darmanis S, Prakadan S, Ziegler C, Lundberg M, Fredriksson S, Hong J, Regev A, Livak K, Landegren U and Shalek A. (2016) Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. Genome Biology, 17:188 DOI 10.1186/s13059-016-1045-6
Article link>

Goncalves I, Edsfeldt A, Colhoun H, Shore A, Palombo C, Natali A, Nordin Fredrikson G, Björbacka H, Wigren M, Bengtsson E, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Gates P, Khan F, Looker H, Adams F, Belch J, Pinnola S, Venturi E, Kozakova M, Gan L, Schnecke C and Nilsson J. (2016) Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes. BMC Cardiovascular Disorders, 16:171 DOI 10.1186/s12872-016-0346-8
Article link>

Gonçalves I, Hultman K, Dunér, P, Edsfeldt A, Hedblad B, Nordin Fredrikson G, Björkbacka H, Nilsson J and Bengtsson E. (2016) High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.  Open Heart.  3: doi:10.1136
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Grönberg C, Asciutto G, Persson A, Nordin Fredrikson G, Nilsson J, Gonçalves I and Björkbacka H. (2016) Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up. Cytokine, doi.org/10.1016/j.cyto.2016.06.009
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Huang B, Svensson P, Ärnlov J, Sundström J, Lind L and Ingelsson E. (2016) Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies. Atherosclerosis, 10.1016/j.atherosclerosis.2016.09.014
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Jahn L , Lee Hartline, Nagashree Rao, Brent Logan, Justin J Kim, Kevin Aylor , Li-Ming Gan, Helena U Westergren, and Eugene J Barrett. (2016) Insulin enhances endothelial function throughout the arterial tree in healthy but not metabolic syndrome subjects. J. Clin. Endocrinol. Metab.  doi: 10.1210/jc.2015-3293
PubMed link >

Kaihola H, Yaldir F, Hreinsson J, Hörnaeus K, Bergquist J, Olivier J, Åkerud H and Sundström-Poromaa I. (2016) Effects of Fluoxetine on Human Embryo Development. Frontiers in Cellular Neuroscience, doi: /10.3389/fncel.2016.00160
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Lind L, Sundström J, Stenmo M, Hagström E and Ärnlöv J. (2016) Discovery of new biomarkers for atrial fibrillation using a custom-made proteomics chip. Heart, 10.1136/heartjnl-2016-309764
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Loskog A, Maleka A, Mangsbo S, Svensson E, Lundberg C, Nilsson A, Krause J, Agnarsdottir M, Sundin A, Ahlström H, Tötterman T and Ullenhag G. (2016) Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients. British Journal of Cancer  114, 872–880. doi:10.1038/bjc.2016.42
Article link >

Lund N, Gränsbo, K, Wernersson C and Melander O. (2016) Cardiometabolic biomarkers are predictors of readmission and death in patients hospitalized for acute dyspnea  Am. J. Emergency Med., http://dx.doi.org/10.1016/j.ajem.2016.12.048
Article link >

Mailankody S, Devlin S, Korde N, Lendvai N, Lesokhin A, Landau H, Hassoun H, Ballagi A, Ekman D, Chung D, Patel M, Koehne G, Giralt S and Landgren O. (2016) Protein profiling in plasma cell disorders: a feasibility study. Leukemia & Lymphoma, DOI: 10.1080/10428194.2016.1258699
PubMed link>

Moen A, Lind A-L, Thulin M, Kamali-Moghaddam M, Røe C, Gjerstad J and Gordh T. (2016) Inflammatory serum protein profiling of patients with lumbar radicular pain one year after disc herniation. Int. J. Inflammation  Article ID 3874964.
Article link >

Schiopu A, Bengtsson E, Goncalves I, Nilsson J, Nordin Fredrikson G and Björbacka H. Associations Between Macrophage Colony-Stimulating Factor and Monocyte Chemotactic Protein 1 in Plasma and First-Time Coronary Events: A Nested Case–Control Study. (2016) J. Am Heart Assoc., 10.1161/JAHA.115.002851
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Schneiderova P, Pika T, Gajdos P, Fillerova R, Kromer P, Kudelka M, Minarik J, Papajik T, Scudla V and Kriegova E. Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma. (2016) Oncotarget.
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Shaw P, Yang Y, Gonzalez J, Kuruvilla S, Gottbrecht M, Epstein F,Gan L, Keeley E, Kramer C, Salerno M. Extracellular volume by CMR is associated with serum biomarkers of extracellular matrix turnover and inflammation in hypertensive heart disease. Journal of Cardiovascular Magnetic Resonance (2016)  doi:10.1186/1532-429X-18-S1-O103
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Söderlund S, Christiansson L, Persson I, Hjorth-Hansen H, Richter J, Simonsson B, Mustjoki S, Olsson-Strömberg U and Loskog A. Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli. (2016) Leukemia Research, DOI: 10.1016/j.leukres.2016.09.019
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Westergren H, Svedlund S, Momo R, Blomster J, Wåhlander K, Rehnström E, Greasley P, Regina Fritsche‑Danielson R, Oscarsson J and Gan L-M. Insulin resistance, endothelial function, angiogenic factors and clinical outcome in non‑diabetic patients with chest pain without myocardial perfusion defects. Cardiovasc Diabetol (2016) 15:36 DOI 10.1186
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Yang X, Tang Y, Alt, R, Xie, X and Lia, F. Emerging techniques for ultrasensitive protein analysis. Analyst (2016), 10.1039/C6AN00059B. (Review article).
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2015

Asciutto G, Dias NV, Edsfeldt A, Nitulescu M, Persson A, Nilsson M, Dunér P, Nilsson J, Gonçalves I. Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke. PLoS One. (2015) Mar 24;10(3):e0121086. doi: 10.1371/journal.pone.0121086.
PubMed link >

Chen H, Zucknick M, Werner S, Knebel P, Brenner H. Head-to-Head Comparison and Evaluation of 92 Plasma Protein Biomarkers for Early Detection of Colorectal Cancer in a True Screening Setting. Clin Cancer Res. (2015) Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051. Epub 2015 May 26.
PubMed link >

Christiansson L, Söderlund S, Mangsbo S, Hjort-Hansen H, Höglund M, Markevärn B, Richter J, Stenke L, Mustjoki S, Loskog A, Olsson-Strömberg U. The tyrosine kinase inhibitors imatinib and dasatinib reduce myeloid suppressor cells and release effector lymphocyte responses. Mol Cancer Ther. (2015) May;14(5):1181-91. doi: 10.1158/1535-7163.MCT-14-0849.
PubMed link >

Enroth S, Bosdotter Enroth S, Johansson Å, Gyllensten U. Effect of genetic and environmental factors on protein biomarkers for common noncommunicable disease and use of personally normalized plasma protein profiles (PNPPP). Biomarkers. (2015) Sep;20(6-7):355-64. doi: 10.3109/1354750X.2015.1093546.
PubMed link >

Enroth S, Enroth SB, Johansson Å, Gyllensten U. Protein profiling reveals consequences of lifestyle choices on predicted biological aging. Sci Rep. (2015) Dec 1;5:17282. doi: 10.1038/srep17282
PubMed link >

Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Strain D, Kahn F, Looker HC, Adams F, Belch J, Pinnoli S, Venturi E, Kozakova M, Gan LM, Schnecke V, Nilsson J. Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes. Arterioscler Thromb Vasc Biol. (2015) May 7. pii: ATVBAHA.115.305631.
PubMed link >

Greenwood C, Ruf D, Kirvell S, Johnson G, Dhillon HS, Bustin SA. Proximity assays for sensitive quantification of proteins. Biomol Det and Quantif. (2015). 4:10-16.
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Helseth R, Weiss T, Opstad T, Siegbahn A, Solheim S, Freynhofer M, Huber K, Arnesen H and Seljeflot S. Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction. Thrombosis Res. (2015), 136: 1240-1244
PubMed link >

Isgren A, Jakobsson J, Pålsson E, Ekman C J, Johansson A G.M., Sellgren C, Blennow K, Zetterberg H and Landén M. Increased cerebrospinal fluid interleukin-8 in bipolar disorder patients associated with lithium and antipsychotic treatment. Brain Behav Immun. (2015) Jan;43:198-204. doi: 10.1016/j.bbi.2014.10.001. Epub 2014 Oct 14.
PubMed link >

Kalla R, Kennedy NA, Hjelm F, Modig E, Sundell M, Söderholm J, Andreassen B, Bergemalm D, Ventham NT, Hjortswang H, Petr R, Vatn MH, Halfvarson J, Gullberg M, Satsangi J. OC-015 Proximity extension assay technology identifies novel serum biomarkers for predicting inflammatory bowel disease: IBD character consortium. Gut (2015);64:A8 doi:10.1136/gutjnl-2015-309861.15
Article link >

Kaudewitz D, Skroblin P, Bender LH, Barwari T, Willeit P, Pechlaner R, Sunderland NP, Willeit K, Morton A, Armstrong PC, Chan MV, Lu R, Yin X, Gracio F, Dudek K, Langley S, Zampetaki A, de Rinaldis E, Ye S, Warner TD, Saxena A, Kiechl S, Storey R, Mayr M. Association of MicroRNAs and YRNAs with Platelet Function. Circ Res. (2015) Feb 5;118(3):420-32. doi: 10.1161/CIRCRESAHA
Pubmed link >

Larsson A, Carlsson L, Gordh T, Lind A-L, Thulin M, Kamali-Moghaddam M. The effects of age and gender on plasma levels of 63 cytokines. Clin Cancer Res. (2015) Jul 15;21(14):3318-26. doi: 10.1158/1078-0432.CCR-14-3051.
PubMed link >

Larsson A, Carlsson L, Lind A-L, Gordh T, Bodolea C, Kamali-Moghaddam M, Thulin M. The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid. Cytokine. (2015) Jul 15. pii: S1043-4666(15)30020-X. doi: 10.1016/j.cyto.2015.07.010.
PubMed link >

Lind L, Ärnlöv J, Lindahl B, Siegbahn A, Sundström J, Ingelsson E. Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis. Atherosclerosis. 2015 Jul 14;242(1):205-210. doi: 10.1016/j.atherosclerosis. (2015).07.023.
PubMed link >

Lind L, Siegbahn A, Lindahl B, Stenemo M, Sundström J, Ärnlöv J. Discovery of new risk markers for ischemic stroke using a novel targeted proteomics chip. Stroke. (2015) Dec;46(12):3340-7. doi: 10.1161/STROKE AHA.115.010829
PubMed link >

Mahboob S, Ahn SB, Cheruku HR, Cantor D, Rennel E, Fredriksson S, Edfeldt G, Breen EJ, Khan A, Mohamedali A, Muktadir MG, Ranganathan S, Tan S-H, Nice E, Baker MS. A novel multiplexed immunoassay identifies CEA, IL-8 and prolactin as prospectivemarkers for Dukes’ stages A-D colorectal cancers. Clinical Proteomics (2015) Apr 8;12(1):10. doi:10.1186/s12014-015-9081-x. eCollection 2015.
PubMed link >

Miclescu AA, Svahn M, Gordh TE. Evaluation of the protein biomarkers and the analgesic response to systemic methylene blue in patients with refractory neuropathic pain: a double-blind, controlled study. J Pain Res. (2015) Jul 15;8:387-97. doi: 10.2147/JPR.S84685. eCollection 2015.
PubMed link >

Nowak C, Sundström J, Gustafsson S, Giedraitis V, Lind L, Ingelsson E, Fall T.Protein biomarkers for insulin resistance and type 2 diabetes risk in two large community cohorts. Diabetes. (2015) Sep 29. pii: db150881.
PubMed link >

Wigren M, Rattik S, Hultman K, Björkbacka H, Nordin-Fredrikson G, Bengtsson E, Hedblad B, Siegbahn A, Goncalves I, Nilsson J. Decreased levels of stem cell factor in subjects with incident coronary events. J Intern Med. (2015) Oct 14. doi: 10.1111/joim.12443.
PubMed link >

Wiklund K, Gränsbo K, Lund N, Peyman M, Tegner L, Toni-Bengtsson M, Wiel M, Melander O. Inflammatory biomarkers predicting prognosis in patients with acute dyspnea. Am. J. Emerg. Med. (2015) doi: 10.1016/j.ajem.2015.10.052.
PubMed link >


2014

Assarsson E, Lundberg M, Holmquist G, Björkesten J, Thorsen SB, Ekman D, Eriksson A, Rennel Dickens E, Ohlsson S, Edfeldt G, Andersson A-C, Lindstedt P, Stenvang J, Gullberg M, and Fredriksson S. Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability. PLOS one. April 24, (2014).
Article link >

Enroth S, Johansson Å, Bosdotter Enroth S and Ulf Gyllensten U. Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. Nature Commun. (2014) Aug 22;5:4684. doi: 10.1038/ncomms5684.
PubMed link >

Hillered L, Dahlin AP, Clausen F, Chu J, Bergquist J, Hjort K, Per Enblad P and Lewén A. Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting – a technical approach. Front Neurol. (2014); 5: 245.
PubMed link >

Rattik S, Wigren M, Björkbacka H, Nordin Fredriksson G, Hedblad B, Siegbahn A, Bengtsson E, Schiopu A, Edsfeldt A, Dunér P, Grufman H, Concalves I and Nilsson J. High Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events. Arterioscler Thromb Vasc Biol. (2015) Jan;35(1):222-8. doi: 10.1161/ATVBAHA.114.304369,  Epub 2014 Oct 30.
PubMed link >

Solier C, Langen H. Antibody-based proteomics and biomarker research – current status and limitations. Proteomics. (2014) Mar;14(6):774-83. doi: 10.1002/pmic.201300334.
PubMed link >

Publications for studies in non-human species

2022

Kumawat AK, Zegeye M, Paramel GV, et al. Inhibition of IL17A Using an Affibody Molecule Attenuates Inflammation in ApoE-Deficient Mice. (2022) Frontiers in Cardiovascular Medicine, DOI: 10.3389/fcvm.2022.831039
Article link>

2021

Buitrago-Molina L, Pietrek J, Noyan F, et al. Treg-specific IL-2 therapy can reestablish intrahepatic immune regulation in autoimmune hepatitis. (2021) Journal of Autoimmunity, DOI: 10.1016/j.jaut.2020.102591
Article link>

2020

Bue M, Leth Bergholt N, Kruse Jensen L, et. al. Inflammatory proteins in infected bone tissue – An explorative porcine study. (2020) Bone Reports, DOI: 10.1016/j.bonr.2020.100292
Article link>

Dommel S, Berger C, Kunath A, et. al. The Fabp4-Cre-Model is Insufficient to Study Hoxc9 Function in Adipose Tissue. (2020) Biomedicines, DOI: 10.3390/biomedicines8070184
Article link>

Kiouptsi K, Pontarollo G, Todorov H, et. al. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice. (2020) Gut Microbes, DOI: 10.1080/19490976.2020.1767463
Article link>

2019

Li Z, Rasmussen T, Rasmussen M, Li J, Henríquez Olguín C, Kot W, Nielsen D and Jensen T. The Gut Microbiome on a Periodized Low-Protein Diet Is Associated With Improved Metabolic Health.  (2019) Frontiers in microbiology, DOI: 10.3389/fmicb.2019.00709
Article link>

Taylor M, Hughes A, Walton J, Coenen-Stass A, Magiera L, Mooney L, Bell S, Staniszewska A, Sandin L, Barry S, Watkins A, Carnealli L and Hardaker E. Longitudinal immune characterization of syngeneic tumor models to enable model selection for immune oncology drug discovery. (2019) Journal for Immunotherapy of Cancer, DOI: 10.1186/s40425-019-0794-7
Article link>

2018

Löfgren M, Svala E, Lindahl A, Skiöldebrand E and Ekman S. Time-dependent changes in gene expression induced in vitro by interleukin-1β in equine articular cartilage. (2018) Research in Veterinary Science, doi.org/10.1016/j.rvsc.2018.04.013
Article link>

2015

Pauk M, Grgurevic L, Brkljacic J, Kufner V Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt J, Lin H, Volarevic S and Vukicevic S. Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice (2015) International Orthopaedics, doi: 10.1007/s00264-014-2550-4
PubMed link>

2947

Biomarker assays

~881 million

Protein data points generated

940

Publications listed on website

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